Simple strategy for the detection of the amoxicillin antibiotic in different matrices using a low-cost paper electrode

Fast sequential determination of amoxicillin and clavulanate in pharmaceutical samples using batch injection analysis with amperometric detection

“…Following the protocol above, the number of electrons were estimated in one and two for the first and second oxidation peaks for AMX, respectively, and only one electron for the oxidation peak of CLA. The electron number involved in the first oxidation of AMX is consistent with the values previously reported by other researchers in their own studies, as presented in Scheme 1 [1, 32, 36, 40–42]. It was not possible to propose a mechanism for the second oxidation peak of AMX due to uncertainty regarding the dependence on the number of protons.…”

“…Following the protocol above, the number of electrons were estimated in one and two for the first and second oxidation peaks for AMX, respectively, and only one electron for the oxidation peak of CLA. The electron number involved in the first oxidation of AMX is consistent with the values previously reported by other researchers in their own studies, as presented in Scheme 1 [1,32,36,[40][41][42] the CLA oxidation peak can be attributed to the oxygen of the heteroatom of the five-membered ring (oxazole ring), as this heteroatom does not undergo protonation in the pH range evaluated [31]. Furthermore, the radical cation generated in oxidation process can be stabilized by resonance with the allyl group to which it is attached.…”

Electrochemical monitoring of levofloxacin using a silver nanoparticle-modified disposable device based on a lab-made conductive ink

“…The transparent sheet was then cleaned with ethanol and the stencil was adhered to its surface. Then, a lab-made CI composed of 1 g of graphite powder, 1 g of nail polish and 3 mL of acetone mixed in a magnetic stirrer for 30 min, whose composition was previously optimized by our research group, 28 was applied with the aid of a brush over the stencil and it was filled. Finally, the stencil was removed and the electrodes were dried in an oven at (40 ± 5) °C.…”

Development and validation of spectrophotometric method and paper-based microfluidic devices for the quantitative determination of Amoxicillin in pure form and pharmaceutical formulations

“…Amoxicillin (6-(p-hydroxy-alpha-amino phenyl acetamido) penicillanic acid) belongs to the aminopenicillin group penicillin antibiotic [ 11 ]. It is a white powder with sulphureous odor and has a water solubility of 958 mg mL −1 [ 12 ].…”