Simple Method for Incorporating Prior Parameter Information during Model-Based D-Optimal Design of Experiments for Multi-Response Chemical Process Models
Lauren A. Gibson,
Fei F. Liu,
Thomas J. Harris
et al.
Abstract:Fundamental models are important for design, control, and optimization of chemical systems but often contain many unknown parameters that require estimation from experimental data. Model-based design of experiments (MBDoE) can be used to plan experiments, leading to accurate parameter estimates and improved model predictions. Computation of MBDoE objective functions is challenging for nonlinear models with many parameters due to a singular Fisher information matrix. Bayesian approaches can be used to overcome … Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.