Simple Extraction of Bisphenol A in Beverages and Water by Membrane-Protected Liquid Phase Microextraction

Abstract

Bisphenol A (BPA) is a xenoestrogen that widely used in manufacture of plastics. Concern is mounting up when the application of BPA is widespread. A simple sample pre-treatment technique termed membrane-protected liquid phase microextraction (MP-LPME) combined with high performance liquid chromatography (HPLC)-fluorescence detection (FD) was developed for the determination of BPA in beverages and environmental water samples. The MP-LPME technique utilized a nylon membrane to hold the extractant (1-octanol) and prevent the extractant from dissolution into sample solution during agitation. Under optimal extraction conditions, the MP-LPME-HPLC-FD demonstrated ultratrace detection of BPA and insignificant matrix effect extraction with good relative recoveries in the range of 87.1-99.7% from spiked beverage and environmental water samples. The membrane can be reapplied in the MP-LPME after the first usage and offered relative recovery of > 94%. The MP-LPME technique is eco-friendly as it consumes only minute amounts of organic solvent which is supportive to green analysis.

A systematic review on bisphenols – Sources, health impacts, and analytical determination of bisphenol A in aqueous samples

“…The membrane was immersed into the sample for extraction of the analyte., This technique provides cheap and simple extraction. The limitation of this technique is the low membrane re‐useability [55]. A flow‐based liquid‐liquid microextraction process is proposed for the preconcentration and separation of BPA.…”

“…HPLC‐FLD was used for the determination of BPA in beverages and environmental water samples with good relative recoveries in the range of 87.1%–99.7%. [55]. HPLC coupled with a Photodiode array detector was used to detect the presence of BPA in 15 samples of Bottled drinking water and beverages [84].…”