simmr: An open-source tool to perform simulations in Mendelian Randomization
Noah Lorincz-Comi,
Yihe Yang,
Xiaofeng Zhu
Abstract:Mendelian Randomization (MR) has become a popular tool for inferring causality of risk factors on disease. There are currently over 45 different methods available to perform MR, reflecting this extremely active research area. It would be desirable to have a standard simulation environment to objectively evaluate the existing and future methods. We present simmr, an open-source software for performing simulations to evaluate the performance of MR methods in a range of scenarios encountered in practice. Research… Show more
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