“Similia Similibus Curentur”: The scientific grounding of the homeopathic therapeutic principle through the systematic study of the rebound effect of modern drugs

Brain Wave Oscillations as an Objective Neurophysiological Biomarker of Homeopathic Subjective Well-Being

“…Another similar experimental RCT investigated the effect of Histamine 30c on arousal through changes in the sleep patterns of rats, finding that the mean delta band spectral density was lower in the treatment groups than the placebo group. 40 Thus, a change in brain frequencies in accordance with the recognized principle of therapeutic similitude (drug biphasic action) [5][6][7][8] was seen, since the known therapeutic effects on the sleep pattern of the homeopathic medicines Coffea cruda (drowsiness) and Histaminum (sleeplessness) were observed in the increase and decrease of the delta EEG frequency respectively.…”

“…This secondary, vital, homeostatic, or paradoxical reaction of the body might also be described scientifically by means of the rebound effect of modern drugs, which might cause iatrogenic events after discontinuation of antipathic or palliative treatment. [5][6][7][8] Hahnemann attributed great importance to the mental and psychological state of the patient in both the etiopathogenesis of acute and chronic diseases and in the obstacles to their cure. Specifically, Hahnemann referred to the patient's "moral and intellectual character" or "the state of his disposition and mind" (Organon, paragraphs 5 and 208).…”

“Genomic Homeopathy” proposal: use of auto-isotherapic of DNA as a modulator of gene expression in chronic diseases

“…Homeopathic treatment is based on four scientific assumptions (principle of therapeutic similitude, homeopathic pathogenetic trials, prescription of individualized medicines in dynamized doses) validated in different lines of research 1,2 . Employing the principle of therapeutic similitude 3,4 as the central nucleus, homeopathy administers individualized medicines (according to the totality of symptoms) in dynamized doses (ultra-diluted and potentized), which cause similar disorders to those intended to be treated (homeopathic pathogenetic trials) 5,6 , with the aim of stimulating a vital (homeostatic) reaction of the body against its own illnesses.…”

“Homeopathy is not placebo effect”: proof of the scientific evidence for homeopathy

“…Next, the principle of therapeutic similitude is approached according to the homeopathic model and modern pharmacology in the chapter "Fundamentação farmacológica do princípio da similitude" ("Pharmacological basis of the principle of similitude"), describing hundreds of experimental and clinical studies that substantiate the curative response (vital reaction) of homeopathic treatment in accordance with the rebound effect of modern drugs (paradoxical reaction of the organism). Furthermore, it describes the proposal to use modern drugs according to the therapeutic similarity, using the rebound effect of drugs in a therapeutic way [15][16][17] .…”