Similarities in Drinking Behavior of Twin’s Friends: Moderation of Heritability of Alcohol Use

Poelen, Evelien A. P.; Engels, Rutger C. M. E.; Boomsma, Dorret I.; Willemsen, Gonneke

doi:10.1007/s10519-008-9250-z

Cited by 7 publications

(6 citation statements)

References 33 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Other studies have found no gender differences (Alati et al, 2014;McGue, Malone, Keyes, & Iacono, 2014;Poelen, Scholte, Willemsen, Boomsma, & Engels, 2007), and at least one study demonstrated stronger effects of parental drinking for boys (Cleveland & Wiebe, 2003).…”

Section: The Relationship Between Parent Heavy Episodic Drinking and mentioning

confidence: 91%

“…Many longitudinal studies lack information about father's drinking, or average reports across parents for analysis (Donovan & Molina, 2014;Duncan, Gau, Duncan, & Strycker, 2011;Latendresse et al, 2008). Amongst studies that do examine the role of both mother's and father's drinking, some show that only mother's drinking is significantly associated with adolescent drinking after controlling for father's drinking (Chassin, Pillow, Curran, Molina, & Barrera Jr, 1993;Macleod et al, 2008;Poelen et al, 2007). Others report statistically significant coefficients for both parents (Alati et al, 2014;Chassin, Curran, Hussong, & Colder, 1996;Haugland et al, 2015;Kelly et al, 2016;McGue et al, 2014;van der Zwaluw et al, 2008), but do not explicitly test whether the mother's or the father's drinking has stronger associations with adolescent drinking.…”

Section: The Relationship Between Parent Heavy Episodic Drinking and mentioning

confidence: 99%

See 1 more Smart Citation

The Relationship Between Parent Drinking and Adolescent Drinking: Differences for Mothers and Fathers and Boys and Girls

Homel

Warren

2019

Substance Use & Misuse

View full text Add to dashboard Cite

Background: Gender differences in the relationship between parent drinking and adolescent drinking are poorly understood. As parental alcohol use is a primary early exposure to alcohol for adolescents, it is important to understand how consequences may differ for adolescent males and females. Objectives: The aim of this paper was to examine gender differences in the relationship between mother's and father's heavy episodic drinking, and its combination, and adolescent drinking. Methods: The sample included 2,800 14-15 year olds (48.9% female) living in two-parent households from the Longitudinal Study of Australian Children. The adolescent outcome measure was having had an alcoholic drink in the past year. Mothers and fathers self-reported their frequency of heavy episodic drinking. Covariates included parents' education, smoking, non-English-speaking background, and symptoms of psychological distress. Logistic regression was used to examine the hypotheses. Results: After adjustment for covariates, both mothers' and fathers' heavy episodic drinking significantly increased the likelihood of adolescent drinking. Moreover, fathers' heavy drinking was more strongly related to adolescent drinking for girls. However, there were no gender differences in the relationship between mothers' drinking and adolescent drinking, and the combination of mothers' and fathers' drinking was not more risky than heavy drinking in either parent alone. Conclusions: Parent heavy episodic drinking is a risk factor for adolescent drinking, after controlling for potential confounding variables. Results suggest that girls may be especially vulnerable to parent heavy drinking in early adolescence. This variation should be considered in the design and evaluation of family-based interventions to prevent adolescent drinking.

show abstract

Section: The Relationship Between Parent Heavy Episodic Drinking and mentioning

confidence: 91%

Section: The Relationship Between Parent Heavy Episodic Drinking and mentioning

confidence: 99%

The Relationship Between Parent Drinking and Adolescent Drinking: Differences for Mothers and Fathers and Boys and Girls

Homel

Warren

2019

Substance Use & Misuse

View full text Add to dashboard Cite

show abstract

“…Twin and family studies have consistently suggested that alcohol-related phenotypes are genetically influenced, with heritability estimates for alcohol abuse and dependence estimated at ~50–60% [2–4]; estimates for other alcohol-related phenotypes are sometimes lower [5–7]. The heritability of alcohol use typically increases beyond adolescence [8, 9].…”

Section: Introductionmentioning

confidence: 99%

Genomic influences on alcohol problems in a population-based sample of young adults

et al. 2015

View full text Add to dashboard Cite

Aims Alcohol problems (AP) contribute substantially to the global disease burden. Twin and family studies suggest that AP are genetically influenced, though few studies have identified variants or genes that are robustly associated with risk. This study identifies genetic and genomic influences on AP during young adulthood, which is often when drinking habits are established. Design We conducted a genome-wide association study of AP. We further conducted gene-based tests, gene ontology analyses, and functional genomic enrichment analyses to assess genomic factors beyond single variants that are relevant to AP. Setting The Avon Longitudinal Study of Parents and Children, a large population-based study of a UK birth cohort. Participants Genetic and phenotypic data were available for 4304 participants. Measurements The AP phenotype was a factor score derived from items from the Alcohol Use Disorders Identification Test, symptoms of DSM-IV alcohol dependence, and three additional problem-related items. Findings One variant met genome-wide significance criteria. Four out of 22,880 genes subjected to gene-based analyses survived a stringent significance threshold (q< .05); none of these have been previously implicated in alcohol-related phenotypes. Several biologically plausible gene ontologies were statistically over-represented among implicated SNPs. SNPs on the Illumina 550K SNP chip accounted for ~5% of the phenotypic variance in AP. Conclusions Genetic and genomic factors appear to play a role in alcohol problems in young adults. Genes involved in nervous system-related processes, such as signal transduction and neurogenesis, potentially contribute to liability to alcohol problems, as do genes expressed in non-brain tissues.

show abstract

“…Research has also examined more refi ned Gene × Environment interactions. For example, one study indicated that genetic factors were more predictive of alcohol use in twin pairs than the twins ' association with peers who drank alcohol (see Poelen, Engels, Scholte, Boomsma, & Willemsen, 2009 ). Another, more recent study ( Larsen et al, 2010 ) examined college students in the Netherlands and found a relationship between the DRD4 7-repeat polymorphism and sensitivity to other students ' drinking behaviors.…”

Section: Examination Of Genetic Overlap In Addictive Behaviors Among ...mentioning

confidence: 99%

The addiction syndrome and the college setting: Prevention.

Borsari¹

2012

APA Addiction Syndrome Handbook, Vol. 2: Recovery, Prevention, and Other Issues.

View full text Add to dashboard Cite

Exposure to the college setting in and of itself is not suffi cient to cause addiction. Therefore, other vulnerabilities or traits must result in addiction to a variety of substances or behaviors. Alcohol use, smoking, marijuana use, and gambling are the four most common addictive behaviors that have received the most research and prevention attention in the college setting. I explore each and propose that they are expressions of the addiction syndrome.Alcohol use. Alcohol use is very prevalent in the college setting and has been identifi ed as a major public health concern ( Fiore et al., 2000 ; National Institute on Alcohol Abuse and Alcoholism, 2002 ). Large-scale surveys have indicated that approximately 68% of all college students drank alcohol in the past month ( Johnston, O ' Malley, Bachman, & Schulenberg, 2006 ), and 40% of college students engage in heavy episodic drinking, defi ned as drinking fi ve or more drinks for men and four or more for women in one episode in the past 2 weeks ( Wechsler, Davenport, Dowdall, Moeykens, & Castillo, 1994 ). Recent reports have indicated that alcohol use by college students has increased over the past decade ( Hingson, Edwards, Heeren, & Rosenbloom, 2009 ), and recent cross-sectional data evidenced a 16% increase in the proportion of students who engage in frequent heavy episodic drinking (three or more in the past 2 weeks) between 1993( Casais et al., 2007. Heavy episodic drinking is related to numerous alcohol-related consequences, including academic diffi culties, property damage, risky sexual activity, blackouts, alcohol poisoning, and death ( Hingson, Heeren, Zakocs, Kopstein, & Wechsler, 2002 ;Jackson, Sher, & Park, 2005 ;Wechsler & Isaac, 1992 ). A survey of more than 14,000 college students revealed that 31% met the criteria for alcohol abuse and 6% met the criteria for alcohol dependence in the previous 12 months ( Knight et al., 2002 ).Smoking. Approximately 30% of the college student population are current smokers (see Patterson, Lerman, Kaufmann, Neuner, & Audrain-McGovern, 2004 , for a review). Smoking is associated with many negative long-term consequences, such as heart attacks, stroke, and high blood pressure ( Centers for Disease Control and Prevention, 2005 ). This behavior has been linked to being White and living in housing that permits smoking ( Patterson et al., 2004 ). In addition, smoking has been associated with collegiate athletic involvement ( Wechsler, Davenport, Dowdall, Grossman, & Zanakos, 1997 ) as well as membership in the Greek system ( Emmons, Wechsler, Dowdall, & Abraham, 1998 ). Rates of students meeting Diagnostic and Statistical Manual of Mental Disorders (4th ed.; DSM-IV ; American Psychiatric Association, 1994 ) criteria for nicotine dependence are diffi cult to determine in college students, given the evidence that dependence can manifest itself at different levels of smoking in different age groups (see Dierker et al., 2008 ). In addition, many college students engage in social smoking (smoke only when others are smoking) a...

show abstract

Similarities in Drinking Behavior of Twin’s Friends: Moderation of Heritability of Alcohol Use

Cited by 7 publications

References 33 publications

The Relationship Between Parent Drinking and Adolescent Drinking: Differences for Mothers and Fathers and Boys and Girls

The Relationship Between Parent Drinking and Adolescent Drinking: Differences for Mothers and Fathers and Boys and Girls

Genomic influences on alcohol problems in a population-based sample of young adults

The addiction syndrome and the college setting: Prevention.

Contact Info

Product

Resources

About