Simethicone for small bowel preparation for capsule endoscopy: a systematic, single-blinded, controlled study

Albert, Jörg; Göbel, Christa-Maria; Leßke, J.; Lotterer, E.; Nietsch, Hubert; Fleig, Wolfgang E.

doi:10.1016/s0016-5107(04)00003-3

Cited by 138 publications

(93 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…At present, although all published papers strongly underlined that small bowel cleanliness is a key point to ensure a complete and accurate examination, and several papers aimed at evaluating factors (dietary restrictions and/or laxatives and/or prokinetic and/or postural tricks) potentially affecting small bowel cleanliness [12,14,16,17,[89][90][91][92][93] have been published, there are still no recommendations about small bowel preparation for capsule endoscopy.…”

Section: Risks and Limitationsmentioning

confidence: 99%

“…Unfortunately about a quarter of published papers are case reports (187) or collections of small case series and 131 published papers are expert reviews. Following the rules of evidence based medicine [9] we can classify these papers at the lowest level of scientific evidence while, among the huge number of publications about capsule endoscopy, there are only 8 randomized controlled studies [five about bowel preparation, 2 about Nonsteroidal anti-inflammatory drugs (NSAIDs) induced damage and 1 about obscure GI bleeding (OGIB)] [10][11][12][13][14][15][16][17] and 4 metanalyses (about OGIB or Crohn's disease) [18][19][20][21] ; all these papers can be ranked as evidence grade 1c.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Small bowel capsule endoscopy in 2007: Indications, risks and limitations

Rondonotti¹

2007

WJG

View full text Add to dashboard Cite

Capsule endoscopy has revoluzionized the study of the small bowel by providing a reliable method to evaluate, endoscopically, the entire small bowel. In the last six years several papers have been published exploring the possible role of this examination in different clinical conditions. At the present time capsule endoscopy is generally recommended as a third examination, after negative bidirectional endoscopy, in patients with obscure gastrointestinal bleeding. A growing body of evidence suggests also an important role for this examination in other clinical conditions such as Crohn's disease, celiac disease, small bowel polyposis syndromes or small bowel tumors. The main complication of this examination is the retention of the device at the site of a previously unknown small bowel stricture. However there are also some other open issues mainly due to technical limitations of this tool (which is not driven from remote control, is unable to take biopsies, to insufflate air, to suck fluids or debris and sometimes to correctly size and locate lesions).The recently developed double balloon enteroscope, owing to its capability to explore a large part of the small bowel and to take targeted biopsies, although being invasive and time consuming, can overcome some limitations of capsule endoscopy. At the present time, in the majority of clinical conditions (i.e. obscure GI bleeding), the winning strategy seems to be to couple these two techniques to explore the small bowel in a painless, safe and complete way (with capsule endoscopy) and to define and treat the lesions identified (with double balloon enteroscopy).

show abstract

Section: Risks and Limitationsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Small bowel capsule endoscopy in 2007: Indications, risks and limitations

Rondonotti¹

2007

WJG

View full text Add to dashboard Cite

show abstract

“…Purgatives appear to be of likely benefit [10][11][12]. Simethicone has been found to decrease intraluminal air bubbles and improve mucosal visibility, [79,80] but has also been shown to be inferior to magnesium citrate in grading of mucosal visibility [81].…”

Section: Poor Visualizationmentioning

confidence: 99%

Video Capsule Endoscopy: The Past, Present, and Future

Whitmer¹

2013

J Gastrointest Dig Syst

View full text Add to dashboard Cite

show abstract

“…Red-colored foods could be avoided because of mimicking GI bleeding. Whether active bowel preparations using polyethylene glycol or simethicone help to improve the diagnostic yields is controversial [11,12]. Water or clear fluids can be taken after 2 hours and food and medication can be taken 4 hours after ingestion of the capsule.…”

Section: The Procedures Of Cementioning

confidence: 99%

The Role of Capsule Endoscopy in the Diagnosis of Crohn's Disease

Rhee

2012

Pediatr Gastroenterol Hepatol Nutr

View full text Add to dashboard Cite

The examination of small bowel in Crohn's disease (CD) is very important. Capsule endoscopy (CE) has been recognized as a good tool for evaluation of small bowel. The capsule placement is achieved endoscopically for Children not to swallow capsule. CE is superior to any other modalities for examination of small-bowel. The large portion of pediatric patients with known CD were found with CE to have more extensive and newly diagnostic small-bowel disease. All of them had therapeutic changes. The most side effect of CE is capsule retention. The capsule retention rate in pediatric CD is about 7.3%. The patency capsule helps to predict the possibility of capsule retention. For the improving of the diagnostic accuracy, the experience of more than 20 readings of CE is needed. (Pediatr Gastroenterol Hepatol Nutr 2012; 15: 8∼12)

show abstract

Simethicone for small bowel preparation for capsule endoscopy: a systematic, single-blinded, controlled study

Cited by 138 publications

References 26 publications

Small bowel capsule endoscopy in 2007: Indications, risks and limitations

Small bowel capsule endoscopy in 2007: Indications, risks and limitations

Video Capsule Endoscopy: The Past, Present, and Future

The Role of Capsule Endoscopy in the Diagnosis of Crohn's Disease

Contact Info

Product

Resources

About