Silver thiolate nanoclusters as support for chiral ligands: application in heterogeneous phase asymmetric catalysis

Abstract

Silver thiolate nanoclusters have been functionalized with a chiral amino alcohol ligand that has previously shown high catalytic efficiency in different asymmetric reactions. The as-developed nanostructured catalyst, which can be...

Advanced Functionalized Nanoclusters (Cu, Ag, and Au) as Effective Catalyst for Organic Transformation Reactions

“…To support chiral ligands, L. Primitivo recently used silver NCs (Ag 38 ) (14). [200] Catalytic effectiveness of the chiral NC catalyst was evaluated by testing it on the Henry reaction after extensive research into refining the condition of reaction to immobilize a chiral amino alcohol ligand onto NCs. Several nitro alcohol compounds were synthesized with large enantiomeric excesses and good yields that were relatively similar to those achieved in the homogeneous phase (Scheme 17).…”

“…Conversely, in homogenous phase asymmetric catalysis, tedious and costly purification processes are required to separate the chiral catalyst from the reaction mixture, preventing the practical application of asymmetric catalysis. To support chiral ligands, L. Primitivo recently used silver NCs (Ag 38 ) (14) [200] . Catalytic effectiveness of the chiral NC catalyst was evaluated by testing it on the Henry reaction after extensive research into refining the condition of reaction to immobilize a chiral amino alcohol ligand onto NCs.…”

Biomimetic Chiral Nanomaterials with Selective Catalysis Activity

“…[ 216 ] Similarly, the chiral amino alcohol ligands modified silver nanoclusters were prepared for non‐homogeneous asymmetric catalysis, which achieved higher ee (70%) than the homogeneous phase (63%). [ 214 ] Inorganic metal NPs after the grafting of chiral selectors had become the candidate catalysis for the applications of heterogeneous enantioselective catalysis. This principle could be extended to the construction of other chiral nanomaterials by applying amino acids as chiral ligands.…”

“…Various artificial chiral nanozymes had been fabricated with chiral ligands such as amino acids for the enantioselective catalysis applications ( Table 1 ). [ 214 ] The development of chiral nanomaterials with intense chiral activity, high selectivity, and well stereocontrol was still a challenge for enantioselective catalysis. In order to increase the chiral recognition, amino acids served as chiral selectors were coated on an inorganic metal NPs surface.…”

BSA-Capped Dual-Emissive Silver Nanoclusters for Detection of IO4– and Cu2+ Ions

“…Metal nanoclusters (MNCs) possessing inherent intriguing features, viz., molecule-like discrete energy levels, ultrasmall size, and remarkable fluorescence (Fl), continue gaining attention among researchers. − Their exceptional inherent properties render them an extensive platform for offering various applications like sensing toxic metal ions − and hazardous molecules, , bioimaging, photodynamic theory, catalysis, and optoelectronics . MNCs, particularly with red or near-infrared (NIR) emission, possess remarkable advantages in contrast to lower wavelength emitting MNCs due to their beneficial properties like deep cell penetrating power, minimizing the possibility of light scattering, and bypassing autofluorescence, − augmenting their utilization for various applications ranging from sensing of environmental contaminants to biologically hazardous molecules. − MNCs capped by proteins offer excellent biocompatibility and optical stability. − Following the first report of bovine serum albumin (BSA)-capped gold nanoclusters (AuNCs), several other proteins, e.g., lysozyme (LYS), ovalbumin, insulin, pea protein, and pepsin, have been utilized for capping many other MNCs.…”