Silver, the magic bullet in dentistry – A review

Bharkhavy, K.V.; Pushpalatha, C.; Anandakrishna, Latha

doi:10.1016/j.matpr.2021.12.200

Cited by 3 publications

(2 citation statements)

References 27 publications

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“…Silver, the natural biocide, is used in medicine since the time of Hippocrates to treat burn wounds because of its antibiotic and wound healing properties. In Dentistry, Silver amalgam had been in use for centuries owing to its superior physical and mechanical properties [4].…”

Section: Introductionmentioning

confidence: 99%

A study of the impact of solid cast removable dentures with silver electroplating on the condition of patients

Nikonov

Krynychko

Bobrovska

et al. 2023

Acta Marisiensis - Seria Medica

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Objectives: The aim of our study was to determine the effectiveness and biocompatibility of the use of solid clasp dentures with silver plating in the restoration of partial defects of the dentition. Methods: The study involved 23 patients with partial secondary adontia after oral rehabilitation. At the first stage, before the start of treatment and after a month of using a clasp prosthesis, patients underwent studies of blood biochemical parameters, Schiller-Pisarev’s test and Papillary-marginal-alveolar index. At the second stage of the research, silver electroplating was applied to the metal parts of the clasp prosthesis and after a month of use, its effect on oral hygiene and blood biochemical parameters was assessed. Results: After installation of the removable prosthesis with solid structures, the PMA index after the use of silver-plated clasp prosthesis decreased to medium severity, which is explained by positive impact on the inflammatory process in the gums. We can see the stability of biochemical parameters of blood in patients with solid removable prostheses can serve as a justification for the administration of silver electroplating for prophylactic and therapeutic purposes. Conclusions: The effectiveness of the use of silver plating in the treatment of partial defects of the dentition eliminates the clinical manifestations of the pathological condition and prevents possible complications in the oral cavity.

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Section: Introductionmentioning

confidence: 99%

A study of the impact of solid cast removable dentures with silver electroplating on the condition of patients

Nikonov

Krynychko

Bobrovska

et al. 2023

Acta Marisiensis - Seria Medica

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“…Such additional effects are attempted by adding metal ions with known antibacterial properties to dental materials. An example is the widely used silver ions, among others, in the form of nanoparticles (AgNPs) [2]. According to the ASTM definition, a nanoparticle is a small particle that ranges between 1 and 100 nm in size.…”

Section: Introductionmentioning

confidence: 99%

Cytotoxicity of Silver-Containing Coatings Used in Dentistry, a Systematic Review

et al. 2022

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Silver is an element that has been widely used in medicine. As a result of its remarkable properties, this metal is now extensively used in virtually all areas of dentistry. Its anti-caries and antibacterial properties are used in (but not limited to) periodontal therapy or during endodontic treatment. The addition of silver ions to materials, such as cements and substances used for fillings, proved to increase their flexural strength and surface microhardness. This element has also found use in orthodontics, e.g., as a material covering components of fixed braces or in implantology as one of the components of coatings applied to dental implants. The following systematic review aims to find and analyze available studies that evaluate silver according to cytotoxicity. For this purpose, information was gathered from three databases: PubMed, Web of Science, and Scopus. This was followed by the Risk of Bias (RoB) analysis and the GRADE analysis of selected articles in which cytotoxicity was tested on human gingival fibroblasts (HGFs). A total of 387 articles were evaluated using required criteria, and, 13 papers were selected for final review. As all studies were evaluated to be of relatively good quality, it may be concluded that silver used in dentistry in low concentrations is free of significant cytotoxicity, and its use helps to improve the properties of the materials used.

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Effect of Traditional Drug Therapy and its Combination with Soderm®-Forte and New Injectable Form of Rexod® on the Antioxidant-prooxidant Red Blood Cell System in Rats with Experimental Periodontitis

Tseluyko

Pavlyuchenko

Leontyev

et al. 2022

Kuban. nauсh. med. vestnik

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Background. The development of periodontitis is strongly linked with both periodontopathogenic microflora and antioxidant-proxidant system disorders, which determines the need for the combined use of antimicrobial and antioxidant agents.Objectives. A comparative evaluation of the antioxidant-prooxidant system of red blood cells in rats with experimental periodontitis against the background of the traditional drug therapy and its combination with Soderm®-Forte and new injectable form of Rexod®.Methods. The authors conducted a comparative study of the effect of traditional drug therapy (TDT) and its combination with Soderm®-Forte gel containing silver nanoparticles, recombinant human superoxide dismutase (Rexod®) and new injectable form (NIF) of Rexod® on the condition of the antioxidant-prooxidant system of red blood cells in rats with experimental periodontitis (EP). The experiments were performed on Wistar male rats of 210–230 g. EP was induced by ligature method. The rats were randomly divided into 5 comparable groups of 12 animals: group 1 — with intact periodontium; group 2 — with EP; group 3 — with EP, where TDT was used, including oral irrigation with chlorhexedine (0.05% solution) and application of Septo-Pack dento-gingival dressing; group 4 — with EP, TDT and Soderm®-Forte gel (applied into the periodontal pockets of the lower incisors); group 5 — with EP, TDT in combination with Soderm®-Forte gel and NIF of Rexod®, which was injected intraperitoneally at a dose of 8000 U/kg. Treatment of rats with EP (groups 3–5) was carried out for 12 days. The observation period for all animals lasted 42 days. The biochemical tests and the antioxidant-prooxidant index were used to assess the condition of antioxidant-prooxidant system. Statistical analysis of the obtained results was carried out with parametric and non-parametric methods of Microsoft Excel (Microsoft, USA), Analysis package and AtteStat, as well as Statistica 8.0 (StatSoft, USA) software.Results. The application of TDT against the developed EP caused a moderate positive correction of the indicators of Antioxidant protection system (APS). The enrichment of TDT for the EP animals with Soderm®-Forte and especially Soderm®-Forte in combination with NIF of Rexod® to enhance the APS potential caused more significant positive dynamics of the balance in the antioxidant-prooxidant system compared to TDT.Conclusion. The combination of TDT with Soderm®-Forte and NIF of Rexod® has the most significant positive corrective effect on the condition of antioxidant-prooxidant system of red blood cells in rats with EP in comparison with the complex of TDT with Soderm®-Forte and TDT used separately.

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Silver, the magic bullet in dentistry – A review

Cited by 3 publications

References 27 publications

A study of the impact of solid cast removable dentures with silver electroplating on the condition of patients

A study of the impact of solid cast removable dentures with silver electroplating on the condition of patients

Cytotoxicity of Silver-Containing Coatings Used in Dentistry, a Systematic Review

Effect of Traditional Drug Therapy and its Combination with Soderm®-Forte and New Injectable Form of Rexod® on the Antioxidant-prooxidant Red Blood Cell System in Rats with Experimental Periodontitis

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