Silver nanoparticles from leaf extract of Mentha piperita: Eco-friendly synthesis and effect on acetylcholinesterase activity

Khatoon, Aisha; Khan, Faraz Idris; Ahmad, Nabeel; Shaikh, Sibhghatulla; Rizvi, Syed Mohd Danish; Shakil, Shazi; Al-Qahtani, Mohammad H.; Abuzenadah, Adel M.; Tabrez, Shams; Ahmed, Ashour M.; Alafnan, Ahmed; Islam, Hayatul; Iqbal, Danish; Dutta, Rajiv

doi:10.1016/j.lfs.2018.08.046

Cited by 87 publications

(43 citation statements)

References 21 publications

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“…It showed that these green synthesis nanoparticles from this plant extract might cause neurotoxicity via inhibiting AChE activity. This activity was confirmed by conduction of enzyme kinetic studies which revealed that silver nanoparticles were capable of binding to both the free AChE enzyme and to the enzyme-substrate (AChE-AChI) complex [58]. Results of this study showed that; due to their small size, nanoparticles may easily cross the blood brain barrier and could interact with various neurological targets, which in turn causes neurotoxic effects.…”

Section: Cytotoxicitysupporting

confidence: 55%

Green synthesis of silver nanoparticles mediated by traditionally used medicinal plants in Sudan

2019

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Sudan has a tremendous wealth flora due to its unique geographical location and diverse climate. Vast records of plants and plants' secondary metabolites are reported to possess redox capacity and can be exploited for the biosynthesis of nanoparticles. Plant-mediated synthesis of silver nanoparticles is preferred due to their availability and their various metabolites. The present review explores the potentiality and diversity of biological activities of silver nanoparticles that originated from the combination of silver and phyto-constituents of mostly traditionally used Sudanese medicinal and aromatic plants. The green synthesis methods of silver nanoparticles mediated by more than 45 traditionally used medicinal plants are critically reviewed. In addition, parameters that affect the synthesis of plant-mediated silver nanoparticles, their characterization techniques and various biological activities are summarized and discussed. Thus, the study of green synthesis of silver nanoparticles and its applications can be extended to involve vast plant diversity of Sudan.

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Section: Cytotoxicitysupporting

confidence: 55%

Green synthesis of silver nanoparticles mediated by traditionally used medicinal plants in Sudan

2019

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“…Antibacterial assessment of synthesized AgNPs was performed primarily by the disk diffusion technique [ 38 ]. However, after the selection of active AgNPs based on preliminary results, minimum inhibitory concentration (MIC) was evaluated by applying the microbroth dilution approach on the microtiter plate [ 39 ]. Escherichia coli (ATCC 25922), Staphylococcus aureus (ATCC 25923), Klebsiella pneumoniae (ATCC 13883), and Micrococcus luteus (ATCC 14593) bacterial strains were procured from the National Chemical Laboratory, India.…”

Section: Methodsmentioning

confidence: 99%

Therapeutic Applications of Biostable Silver Nanoparticles Synthesized Using Peel Extract of Benincasa hispida: Antibacterial and Anticancer Activities

et al. 2020

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The purpose of this study was to fabricate biostable inorganic silver nanoparticles (AgNPs) using fresh peel (aqueous) extract of Benincasa hispida. A fast, robust, and eco-friendly approach was used for the synthesis of AgNPs, where bioactive components of peel extract of B. hispida acted as reducing and stabilizing agents. Synthesized AgNPs were characterized using a UV–Vis spectrophotometer, Fourier-transform infrared spectroscopy (FTIR), dynamic light scattering (DLS), and electron microscopy. The synthesized nanoparticles exhibited maximum absorption at 418 nm under the typical AgNPs surface plasmon resonance band range. They depicted a mean size of 26 ± 2 nm with a spherical shape. Their therapeutic prospective was determined by evaluating their antimicrobial and anticancer potential. The bio-synthesized silver nanoparticles exhibited strong antimicrobial activity with minimum inhibitory concentration (MIC 50) values of 14.5, 8.6, 6.063, and 13.4 μg/mL against Staphylococcus aureus (ATCC 25923), Micrococcus luteus (ATCC 14593), Escherichia coli (ATCC 25922), and Klebsiella pneumonia (ATCC 13883), respectively. The biosynthesized AgNPs showed potent in vitro cytotoxicity against human cervical cancer cell line with a half maximal inhibitory concentration (IC50) value of 0.066 μg/mL; however, no cytotoxic effect was observed on normal human primary osteoblasts cell line. This study explored B. hispida extract and confirmed its effectiveness as a promising source in producing AgNPs that could be employed for several therapeutic applications.

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“…AgNPs synthesized using a chemical method and biogenic AgNPs showed similar toxicity in vitro and in vivo [133]. Furthermore, similar to the chemically synthesized AgNPs, biogenic AgNPs cause neurotoxicity owing to their capability of binding to the free acetylcholine enzyme (AChE) and the enzyme-substrate (AChE-acetylcholine) complex [134].…”

Section: Aunps Several Factors Play Important Roles In De-mentioning

confidence: 97%

Biosynthesis and Potential Applications of Silver and Gold Nanoparticles and Their Chitosan-Based Nanocomposites in Nanomedicine

Katas

Moden

Lim

et al. 2018

Journal of Nanotechnology

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Biosynthesized or biogenic metallic nanoparticles, particularly silver and gold nanoparticles (AgNPs and AuNPs, respectively), have been increasingly used because of their advantages, including high stability and loading capacity; moreover, these nanoparticles are synthesized using a green and cost-effective method. Previous studies have investigated reducing and/or stabilizing agents from various biological sources, including plants, microorganisms, and marine-derived products, using either a one-pot or a multistep process at different conditions. In addition, extensive studies have been performed to determine the biological or pharmacological effects of these nanoparticles, such as antimicrobial, antitumor, anti-inflammatory, and antioxidant effects. In the recent years, chitosan, a natural cationic polysaccharide, has been increasingly investigated as a reducing and/or stabilizing agent in the synthesis of biogenic metallic nanoparticles with potential applications in nanomedicine. Here, we have reviewed the mechanism of biosynthesis and potential applications of AgNPs and AuNPs and their chitosan-mediated nanocomposites in nanomedicine.

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Silver nanoparticles from leaf extract of Mentha piperita: Eco-friendly synthesis and effect on acetylcholinesterase activity

Cited by 87 publications

References 21 publications

Green synthesis of silver nanoparticles mediated by traditionally used medicinal plants in Sudan

Green synthesis of silver nanoparticles mediated by traditionally used medicinal plants in Sudan

Therapeutic Applications of Biostable Silver Nanoparticles Synthesized Using Peel Extract of Benincasa hispida: Antibacterial and Anticancer Activities

Biosynthesis and Potential Applications of Silver and Gold Nanoparticles and Their Chitosan-Based Nanocomposites in Nanomedicine

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