Silver Nanoparticles-Based Substrate for Blood Serum Analysis under 785 nm Laser Excitation

Al-Sammarraie, Sahar Z.; Bratchenko, Lyudmila A.; Typikova, Elena N.; Lebedev, P. A.; Zakharov, Valery P.; Bratchenko, Ivan А.

doi:10.18287/jbpe22.08.010301

Cited by 5 publications

(1 citation statement)

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“…In addition, malignant tissues can be distinguished from benign ones [18,24], or different types of cancer can be classified [25]. Similar to cancer studies, Raman spectroscopy is frequently used to detect infectious [26] and non-infectious [27] diseases. In recent years, there has been considerable progress in detecting disease biomarkers in different body fluids such as blood, saliva, urea, etc., commonly referred to as liquid biopsy [28,29].…”

Section: Introductionmentioning

confidence: 99%

Raman-Based Techniques in Medical Applications for Diagnostic Tasks: A Review

Khristoforova,

Bratchenko,

Bratchenko

2023

IJMS

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Raman spectroscopy is a widely developing approach for noninvasive analysis that can provide information on chemical composition and molecular structure. High chemical specificity calls for developing different medical diagnostic applications based on Raman spectroscopy. This review focuses on the Raman-based techniques used in medical diagnostics and provides an overview of such techniques, possible areas of their application, and current limitations. We have reviewed recent studies proposing conventional Raman spectroscopy and surface-enhanced Raman spectroscopy for rapid measuring of specific biomarkers of such diseases as cardiovascular disease, cancer, neurogenerative disease, and coronavirus disease (COVID-19). As a result, we have discovered several most promising Raman-based applications to identify affected persons by detecting some significant spectral features. We have analyzed these approaches in terms of their potentially diagnostic power and highlighted the remaining challenges and limitations preventing their translation into clinical settings.

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