Silver Nanoparticle-Embedded Nanogels for Infection-Resistant Surfaces

Abstract

The present study aims at fabricating carboxymethyl cellulose (CMC)-functionalized silver nanogel (CMC-Ag nanogel)-immobilized cotton fabric for preventing chronic infections. Silver-embedded CMC nanogels were prepared by the reduction of silver nitrate in the presence of fructose and CMC as the reducing and stabilizing agents, respectively. Various parameters, such as CMC concentration, reduction time, and reduction temperature, having effects on the synthesis were optimized to obtain nanogels. The formation of CMC-Ag nanogels was monitored by ultraviolet–visible (UV–vis) spectroscopy, whereas the size and morphology were investigated by transmission electron microscopy and field emission scanning electron microscopy. An average particle size in the range of 5–10 nm was achieved. Subsequently, nanogel-coated cotton fabric was further investigated for antimicrobial activity against Gram-negative and Gram-positive bacterial strains using zone of inhibition, colony count, and adhesion analyses. Almost complete (>99%) colony reduction was observed at a 300 ppm silver content. The nanogel-coated fabric also showed excellent antiadhesion behavior against Staphylococcus aureus and Escherichia coli. This investigation suggested a promising approach to design antibacterial fabrics for various biomedical applications in the human healthcare sector.

Antimicrobial finishing of polypropylene fabric using bioactive nanogels

“…After the acclimatization period, a skin compatibility study was carried out. [ 7 ] Firstly, hairs on the dorsal region of the mice were shaved, followed by treatment with a skin hair‐remover to achieve a proper and clean shaved area on the dorsal side of the mice. The bio‐functionalized PP fabrics of 20 × 20 mm 2 patch size were then applied on the shaved dorsal site and secured to the skin with transpore adhesive tape.…”

“…Antibacterial studies of the samples were carried out by zone inhibition and colony count methods. [ 7 ] The pristine and nanogel coated PP fabric's antibacterial efficiency was monitored against gram‐positive bacteria S. aureus and gram‐negative bacteria E. coli .…”

“…Choosing suitable antimicrobial agents and coating materials is critical in designing these textiles as bioactive fabrics. [6][7][8] Biopolymers are natural polymers that offer enormous possibilities in different areas of the biomedical field due to their multifunctional structure. Their respective applications are determined by the unique properties they own.…”

Evaluation of Terminalia arjuna loaded in surfactant modified polycaprolactone nanofiber as an infection resistant matrix

“…Glutaraldehyde was used for bacterial fixation, followed by dehydration using an ethanolic gradient solution. The prepared grids were dried adequately prior to TEM analysis 25 …”

Recent Progress in Poly (3,4‐Ethylene Dioxythiophene): Polystyrene Sulfonate Based Composite Materials for Electromagnetic Interference Shielding

“…[ 37,52 ] So, polymer‐based composites with processability, flexibility, and low density have attracted attention as EMI shielding materials. [ 12,40,53–55 ] Polymers are either insulators or intrinsic conductors (ICPs). The primary requirement for EMI shielding material is that it be electrically conductive.…”