Silver-functionalized methyl-silica hybrid materials as antibacterial coatings on surgical-grade stainless steel

Procaccini, Raúl Ariel; Bouchet, Agustina; Pastore, Juan Ignacio; Studdert, Claudia A.; Ceré, Silvia; Pellice, Sergio Antonio

doi:10.1016/j.porgcoat.2016.03.012

Cited by 19 publications

(12 citation statements)

References 36 publications

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“…26 Methyl-modified silica is highly stable in water and even more in seawater, whose pH is limited to the range of 7.5–8.4, with similar methyl-modified silica coatings functionalized with silver ions, for example, currently being considered for as antibacterial coatings on surgical-grade stainless steel. 27 …”

Section: Resultsmentioning

confidence: 99%

Antifouling and Photocatalytic Antibacterial Activity of the AquaSun Coating in Seawater and Related Media

et al. 2017

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Prolonged testing of the new xerogel photocatalytic coating AquaSun applied to a surface probe immersed in ocean water irradiated with simulated solar radiation shows excellent action against biofouling. Activated by moderate solar radiation, the organosilica film has also good antimicrobial properties. Considering the high stability, the environmental footprint, and the low cost of this sol–gel marine coating, the technology has significant potential toward replacing conventional antifouling and foul-release coatings with a single product of broad applicability.

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Section: Resultsmentioning

confidence: 99%

Antifouling and Photocatalytic Antibacterial Activity of the AquaSun Coating in Seawater and Related Media

et al. 2017

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“…Reduction of bacterial adhesion was attributed to increased surface nanoroughness and Si content [94]. While the previous study used ion sputtering to deposit Si ions, other methods used included coating with in situ prepared silver nanoparticles (hybrid organic-inorganic sol-gel material doped with silver) to combat infections while furthering the development of controlled release of antibiotic agents [95]. Magnetron sputtering was also used to generate TiN and TiN/Ag films on SS and TiN/Ag had a higher anti-listerial effect than TiN alone [96].…”

Section: Accepted Manuscriptmentioning

confidence: 99%

Surface modification of stainless steel for biomedical applications: Revisiting a century-old material

Bekmurzayeva

Duncanson

Azevedo

et al. 2018

Materials Science and Engineering: C

191

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Stainless steel (SS) has been widely used as a material for fabricating cardiovascular stents/valves, orthopedic prosthesis, and other devices and implants used in biomedicine due to its malleability and resistance to corrosion and fatigue. Despite its good mechanical properties, SS (as other metals) lacks biofunctionality. To be successfully used as a biomaterial, SS must be made resistant to the biological environment by increasing its anti-fouling properties, preventing biofilm formation (passive surface modification), and imparting functionality for eluting a specific drug or capturing selected cells (active surface modification); these features depend on the final application. Various physico-chemical techniques, including plasma vapor deposition, electrochemical treatment, and attachment of different linkers that add functional groups, are used to obtain SS with increased corrosion resistance, improved osseointegration capabilities, added hemocompatibility, and enhanced antibacterial properties. Existing literature on this topic is extensive and has not been covered in an integrated way in previous reviews. This review aims to fill this gap, by surveying the literature on SS surface modification methods, as well as modification routes tailored for specific biomedical applications.

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“…Antibacterial properties of silver lie in the ability of its ions to damage the cytoplasmic membrane and the respiratory enzymes of bacteria [12]. Nevertheless, the ionic mobility of silver could be extremely fast in sol-gel matrixes, which mean a strong antibacterial behaviour but only at short term [13][14][15]. So, introduction of clay nanoparticles could substantially improve the antibacterial behaviour of this kind of antibacterial coatings through the control of size and shape of silver nanoparticles and the ionic release behaviour [16].…”

Section: Introductionmentioning

confidence: 99%

Epoxy-silica/clay nanocomposite for silver-based antibacterial thin coatings: Synthesis and structural characterization

Mejía

Yohai

Pedetta

et al. 2017

Journal of Colloid and Interface Science

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Development of new functional coatings in the field of health care, as antibacterial applications, deals with a straight control of the diffusive properties that rules the releasing of the active component. In this work, the development of a silver-rich nanocomposite thin coating, loaded with organically modified clay nanoparticles, is presented. The synthesis process included an environment-friendly silanization process of clay nanoparticles (Laponite® S482) with (3-glycidoxypropyl)trimethoxysilane (GPTMS) and the further hydrolytic condensation with tetraethoxysilane (TEOS). Silanization process and the obtained coatings were analysed by Fourier transformed infrared spectroscopy, UV-visible spectroscopy, X-ray diffraction, thermogravimetric curves and scanning electron microscopy. The silanization process of clay nanoparticles with the organically reactive alkyl alkoxysilane, allowed to stabilize and exfoliate the clay nanosheets within a hybrid organic-inorganic sol-gel material. Ring opening of grafted epoxy groups carried to an increasing of the basal spacing, of intercalated clay nanosheets, from 1.3 to 1.8nm. Moreover, incorporation of organically modified clay nanosheets introduced a significant stabilization on the development of silver nanoparticles inside the structure of the nanocomposite coating, retaining the silver inside the coating material and restricting the growing of silver nanoparticles on the surface of the coating. Antibacterial behaviour, against E. coli cultures, performed through agar diffusion tests, provided promising results that allow assuming that the studied nanocomposite coating serves as a reservoir of ionic silver, permitting the antibacterial effect.

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Silver-functionalized methyl-silica hybrid materials as antibacterial coatings on surgical-grade stainless steel

Cited by 19 publications

References 36 publications

Antifouling and Photocatalytic Antibacterial Activity of the AquaSun Coating in Seawater and Related Media

Antifouling and Photocatalytic Antibacterial Activity of the AquaSun Coating in Seawater and Related Media

Surface modification of stainless steel for biomedical applications: Revisiting a century-old material

Epoxy-silica/clay nanocomposite for silver-based antibacterial thin coatings: Synthesis and structural characterization

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