Silver and Gold Nanoparticles for Antimicrobial Purposes against Multi-Drug Resistance Bacteria

Abstract

Several pieces of research have been done on transition metal nanoparticles and their nanocomplexes as research on their physical and chemical properties and their relationship to biological features are of great importance. Among all their biological properties, the antibacterial and antimicrobial are especially important due to their high use for human needs. In this article, we will discuss the different synthesis and modification methods of silver (Ag) and gold (Au) nanoparticles and their physicochemical properties. We will also review some state-of-art studies and find the best relationship between the nanoparticles’ physicochemical properties and potential antimicrobial activity. The possible antimicrobial mechanism of these types of nanoparticles will be discussed in-depth as well.

Nitrogen-fixing Cyanothece sp. as a mixotroph and silver nanoparticle synthesizer: a multitasking exceptional cyanobacterium

“…Indeed, the silver nanoparticles developed in the unfiltered external solution of the cyanobacterial cultures showed indications of many functional groups including peptides as indicated from the functional group bands detected in the FTIR spectroscopy. With regard to the gold nanoparticles, it is suggested that they owe their antimicrobial activity in part to their electrical and optical properties (Rabiee et al, 2022). the antimicrobial superiority of silver nanoparticles over that of gold nanoparticles is mainly attributable to release of silver ions from those nanoparticles unlike gold nanoparticles.…”

Effective and reproducible biosynthesis of nanogold-composite catalyst for paracetamol oxidation

“…The catalytic activity of nanogold-composite was investigated using PCTM in the presence of H 2 O 2 without and with light irradiation. H 2 O 2 served as a source of •OH radicals for PCTM oxidation, and irradiation would enable the photocatalytic activity of the Au NPs (Rabiee et al 2022).…”

A review on contemporary nanomaterial-based therapeutics for the treatment of diabetic foot ulcers (DFUs) with special reference to the Indian scenario

“…Therefore, nanomaterials can be an excellent toolkit for the development of various treatment strategies using different nanoplatforms against multi-drug resistant (MDR) biofilm and planktonic infections. 21 Accordingly, there is an urgent need to discuss the various nanomaterial-based therapies available for preventing AMR and biofilm-related chronic infections, delaying wound healing and ischemic (poor blood flow) disorders, and ultimately preventing limb amputations.…”