2016
DOI: 10.1308/rcsann.2016.0166
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Silicone granuloma from ruptured breast implants as a cause of cervical lymphadenopathy

Abstract: A 56-year-old woman with a 10-year history of bilateral silicone breast implants presented to the ear, nose and throat outpatient clinic with a 2-month history of a right-sided neck lump. She was found to have a 1.3cm supraclavicular lymph node that gave the clinical impression of being reactive. Ultrasonography guided fine needle aspiration was inconclusive and initial review of subsequent computed tomography failed to identify a cause. This was followed by excisional biopsy of the lymph node, which revealed … Show more

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Cited by 15 publications
(15 citation statements)
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“…There are numerous reported cases of silicone lymphadenopathy occurring in the mediastinum and axilla 8 9 12 but there are very few reported cases of silicone associated cervical lymphadenopathy. 5 6 13 Additionally, it is equally rare for saline-based implants to result in regional lymphadenopathy and this case highlights the importance of silicone gel bleeding from the outer silicone lining. Thus, for head and neck specialists it is an important differential diagnosis to consider in patients with any breast implants (since they contain a silicone outer shell).…”
Section: Discussionmentioning
confidence: 86%
“…There are numerous reported cases of silicone lymphadenopathy occurring in the mediastinum and axilla 8 9 12 but there are very few reported cases of silicone associated cervical lymphadenopathy. 5 6 13 Additionally, it is equally rare for saline-based implants to result in regional lymphadenopathy and this case highlights the importance of silicone gel bleeding from the outer silicone lining. Thus, for head and neck specialists it is an important differential diagnosis to consider in patients with any breast implants (since they contain a silicone outer shell).…”
Section: Discussionmentioning
confidence: 86%
“…Presence of extracellular implant in the form of amorphous glassy material is an important clue to the diagnosis. 9,10 Filariasis is an endemic parasitic disease in coastal parts of India. Wuchereria Bancroft is the causative agent in the majority of cases.…”
Section: Resultsmentioning
confidence: 99%
“…Silicone implants are widely used in Europe and the USA for cosmetic purpose. Silicone was initially considered as an inert substance; but was later found to be associated with symptoms like dyspnea, cough, fever, hypoxia, granuloma formation, lymphadenopathy and autoimmune conditions such as connective tissue disorders, fibromyalgia and pulmonary pathologies 5 7 8. These symptoms were described in 2011 by Schoenfeld et al as autoimmune/inflammatory syndrome induced by adjuvants 8 9.…”
Section: Discussionmentioning
confidence: 99%