Silicone Disease (ASIA) - A Case Report

Abstract

The introduction of silicone in aesthetic procedures has raised concerns regarding the possible impacts of silicone on the body. Breast prostheses are still one of the most commonly performed plastic surgeries in Brazil and worldwide despite being linked to numerous complications. Additionally, the use of silicone has been correlated with autoimmune syndrome induced by adjuvant (ASIA), whereby an inflammatory response occurs due to the presence of a substance capable of increasing the immunogenicity of an antigen. This study addresses one such case of ASIA, also known as silicon disease, in order to assess its impact on the daily lives of patients who have undergone a breast prosthetic procedure. Fourteen articles relating to the patient’s case report were analyzed, collected from various platforms, including PUBMED, Scientific Electronic Library Online , Science Direct, and Google Academic. The patient had undergone breast augmentation in 2000. Two years later, she began experiencing symptoms of myalgia, arthralgia, and depression, implicating fibromyalgia. After removal of the prosthesis, the material was biopsied, and it was concluded that an immunological reaction had occurred due to the implant. Since little is known about ASIA, this study aims to increase the understanding of the syndrome and to assist future diagnostics.