Silicon Nanowire Sensors for Bioanalytical Applications: Glucose and Hydrogen Peroxide Detection

α‐Fe2O3 Nanorings Prepared by a Microwave‐Assisted Hydrothermal Process and Their Sensing Properties

“…However, the instability of these electrodes remains a major problem, which is believed by the breaching of enzymes from the electrode surface and the poisoning or loss of activity of the immobilized enzymes. [28] In addition, the enzyme immobilization onto electrodes with the help of other cross-linkers is usually complicated. Herein, we show that the as-formed semiconducting a-Fe 2 O 3 nanorings are potentially suitable for detecting hydrogen peroxide in a physiological system (pH 7.4).…”

Nanotechnology Applications for Chemical and Biological Sensors

“…It has been observed that the sensor response to H 2 gas was fast and resembled a switch with two orders of magnitude change in conductance. Recently, Shao 38 , et al reported that the Si nanowire film modified with can be used as a sensor for glucose detection in aqueous solution. These sensors also show wide linear range (0-10 mM glucose), high sensitivity (172 nA/m Si nanowires showed reversible antibody binding and concentration-dependent detection in real time.…”

Effects of Silicon Nanowires on HepG2 Cell Adhesion and Spreading

“…Their outstanding properties, such as quantum size effects, diameter-dependent thermal conductivity, and large piezoresistance coefficient have attracted a lot of research interest, including for application in biological materials and devices. [13,14] However, before SiNWs can be incorporated into new and existing biomedical devices, their cytotoxicity and potential adverse effects on biological systems should be thoroughly investigated. Here, we report the first study on the cytotoxicity of SiNWs on the human hepatocellular carcinoma cell line, HepG2, and their effect on cell adhesion and spreading.…”

“…[1,2] While there have been reports on the cytotoxicity of carbon nanotubes, [3][4][5][6][7] quantum dots, [8,9] gold nanoparticles, [10] and the biocompatibilities of carbon nanotubes, [11,12] no study has yet appeared on the biological effects of silicon nanowires, which are becoming increasingly important as nanomaterial. [13,14] Silicon nanowires (SiNWs) are one-dimensional nanomaterials that are typically composed of a single crystalline silicon core and an amorphous SiO x sheath. Their outstanding properties, such as quantum size effects, diameter-dependent thermal conductivity, and large piezoresistance coefficient have attracted a lot of research interest, including for application in biological materials and devices.…”

“…[13] HepG2 cells were incubated on the SiNW surface at a density of 3000 cm À2 for 48 h; HepG2 cells incubated on bare silicon wafers were used as control. The adherent cell number on the SiNW surface was counted; the adherent cell percentage was 60.5 % relative to the control.…”