Silicene Quantum Capacitance Dependent Frequency Readout to a Label-Free Detection of DNA Hybridization— A Simulation Analysis

Rahman, Md. Sazzadur; Naima, Rokaia Laizu; Shetu, Khatuna Jannatun; Hossain, Md. Mokarrom; Kaiser, M. Shamim; Hosen, A. S. M. Sanwar; Sarker, Md. Abdul Latif; Ooi, Kelvin J. A.

doi:10.3390/bios11060178

Cited by 3 publications

(6 citation statements)

References 27 publications

(26 reference statements)

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“…In conclusion, it has been inferred that metal decorated silicene can be a potential candidate for distinguishing DNA/RNA nucleobases. Rahman et al [38] have proposed an ISFET model, which is made of silicene and electrolyte layers that help one to detect DNA hybridization. It is to be noted that we would like to mention that DNA hybridization is a process which provides the genetic differences between two organisms.…”

Section: Studies Of Dna Sequencing By Silicenementioning

confidence: 99%

“…In conjunction with the low thermal conductivity of silicene, these findings indicate that silicene-based nanostructures could be the basis of more efficient TE devices. Recently, it has been found that silicene can be used very efficiently as biosensor [38][39][40][41][42].…”

Section: Introductionmentioning

confidence: 99%

“…Their study also revealed the same effectiveness for bio-sensing application of silicene. Rahman et al [38] have compared the sensitivity of both graphene and silicene in order to detect DNA hybridization. They have found that silicene is more effective and efficient in detecting DNA hybridization compare to graphene.…”

Section: Introductionmentioning

confidence: 99%

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A review on transport characteristics and bio-sensing applications of silicene

Ghosal,

Bandyopadhyay,

Chowdhury

et al. 2023

Rep. Prog. Phys.

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Silicene, a silicon counterpart of graphene, hass been predicted to possess massless Dirac fermions.Compared to graphene, the effective spin–orbit interaction is quite significant compared to grapheneand as a result, buckling in silicene opens a gap of 1.55 meV at the Dirac point. This band gap can befurther tailored by applying in plane stress, an external electric field, chemical functionalization anddefects. This special feature allows silicene and its various derivatives as potential candidates fordevice applications. In this short review, we would like to explore the transport features of the pristinesilicene and its possible nano derivatives. Besides, the recent progress in biosensor applications ofsilicene and its hetero-structures will be highlighted.We hope the results obtained from recentexperimental and theoretical studies in silicene will setup a benchmark in diverse applications such asin spintronics, bio-sensing and opto-electronic devices.

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Section: Studies Of Dna Sequencing By Silicenementioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

A review on transport characteristics and bio-sensing applications of silicene

Ghosal,

Bandyopadhyay,

Chowdhury

et al. 2023

Rep. Prog. Phys.

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“…Among them, the most important are fluorescently labeled target microscopy [ 59 ], laser scanner [ 60 ], Surface-Enhanced Raman spectroscopy (SERS) [ 61 , 62 ]; whose methods can be also classified as optical methods. Other well-known methods use enzymatic polymerization [ 63 ], biofunctionalized ion-sensitive field-effect transistors [ 64 ] and varieties of methods based on different imaging systems [ 65 ]. The biomolecules with corresponding tags as enzymatic, fluorescent, radioactive etc.…”

Section: Biosensor Technologymentioning

confidence: 99%

Device Processing Challenges for Miniaturized Sensing Systems Targeting Biological Fluids

Stoukatch

Dupont

Redouté

2022

Biomedical Materials & Devices

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This article presents a review of device processing technologies used in the fabrication of biomedical systems, and highlights the requirements of advanced manufacturing technology. We focus on biomedical systems that perform diagnostics of fluidic specimens, with analytes that are in the liquid phase. In the introduction, we define biomedical systems as well as their versatile applications and the essential current trends. The paper gives an overview of the most important biomolecules that typically must be detected or analyzed in several applications. The paper is structured as follows. First, the conventional architecture and construction of a biosensing system is introduced. We provide an overview of the most common biosensing methods that are currently used for the detection of biomolecules and its analysis. We present an overview of reported biochips, and explain the technology of biofunctionalization and detection principles, including their corresponding advantages and disadvantages. Next, we introduce microfluidics as a method for delivery of the specimen to the biochip sensing area. A special focus lies on material requirements and on manufacturing technology for fabricating microfluidic systems, both for niche and mass-scale production segments. We formulate requirements and constraints for integrating the biochips and microfluidic systems. The possible impacts of the conventional microassembly techniques and processing methods on the entire biomedical system and its specific parts are also described. On that basis, we explain the need for alternative microassembly technologies to enable the integration of biochips and microfluidic systems into fully functional systems.

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“…By using an ion-sensitive field-effect transistor (ISFET) structure with silicene layers and electrolyte, Sazzadur Rahman et al have designed a sensor with the capability of label-free detection of deoxyribonucleic acid (DNA) for disease-related gene expression 37 . Also, Kharadi et al reported an optical detector using silicene-MoS 2 heterojunction with high efficiency 38 .…”

Section: Introductionmentioning

confidence: 99%

First designing of a silicene-based optical MOSFET with outstanding performance

Emami-Nejad

Mir

Lorestaniweiss

et al. 2023

Sci Rep

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Miniaturized integrated optical devices with low power consumption have long been considered hot candidates for plasmonic applications. While 2D materials such as graphene have been proposed for this purpose, they suffer from large propagation loss and low controllability at room temperature. Here, a silicene-based optical MOSFET with excellent performance is designed to achieve integrated circuit optical technology. The designed device is comprised of a silicene optical waveguide whose switching operation is performed by a gate and has a structure similar to an enhancement MOSFET with a formed channel. Unlike graphene, the surface conductivity of silicene can be controlled by both chemical potential and an electric field perpendicular to its surface. This unique feature of silicene is used to design and simulate an optical-MOSFET with transverse electric polarization at 300 K. The salient characteristics of the optical device include its nanoscale dimensions, ultra-low insertion loss of 0.13 dB, infinite extinction ratio, and quality factor of 688, proposing it as a promising tool for optical integration.

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Silicene Quantum Capacitance Dependent Frequency Readout to a Label-Free Detection of DNA Hybridization— A Simulation Analysis

Cited by 3 publications

References 27 publications

A review on transport characteristics and bio-sensing applications of silicene

A review on transport characteristics and bio-sensing applications of silicene

Device Processing Challenges for Miniaturized Sensing Systems Targeting Biological Fluids

First designing of a silicene-based optical MOSFET with outstanding performance

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