Silicate Pneumoconiosis in Camels (<i>Camelus Dromedarius</i> L.)

Hansen, H. J.; Jama, Fatuma M.; Nilsson, Christína; Norrgren, Leif; Abdurahman, O. Sh.

doi:10.1111/j.1439-0442.1989.tb00793.x

Cited by 13 publications

(6 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Furthermore, the chemical composition and crystalline structure of the material were elucidated to determine its origin. The histologic appearance and location of the largely nonfibrotic pneumoconiosis lesions correspond to what have been reported in similar descriptive studies which describe similar findings in dogs, 10,17 kiwis, 53 badgers, 15,51 birds, 7,21,50 camels, 28,32 and a variety of zoo animals 8 with high incidence of pneumoconiosis and associated lesions. 7…”

Section: Discussionsupporting

confidence: 86%

Histology, prevalence, and environmental sources for pulmonary silicates depositions in domestic and wild animals

et al. 2023

View full text Add to dashboard Cite

The source and significance of pulmonary silicate crystals in animals and people are poorly understood. To estimate the prevalence and characterize the pulmonary crystalline material in animals from St. Kitts, tissue samples from dogs, horses, cattle, sheep, goats, pigs, chickens, mongooses, and monkeys were examined by light microscopy, scanning electron microscopy with energy-dispersive x-ray analysis (SEM/EDXA), and x-ray diffraction. Crystalline material was seen in 201 of 259 (77.6%) lung samples as perivascular and interstitial accumulations of heterogeneous crystalline particulate material, free or within macrophages (silicate-laden macrophages [SLMs]), mostly lacking evidence of chronic inflammation or fibrosis. The crystalline material was birefringent, basophilic on acid-fast, and composed of silicas on SEM/EDXA. Mongooses (100%) and monkeys (98%) had the highest prevalence of SLM, followed by cattle and chickens. Lesions were graded on a 3-point scale based on the histologic location and extent of silicates and SLM and were significantly more severe in mongooses (median = 3) than in monkeys (median = 2), dogs (median = 2), and chickens (median = 1). On EDXA, the crystalline material from lungs, air, and topsoil was composed of silicon, oxygen, aluminum, and iron, with a particulate matter size between 2.5 and 10 µm. We hypothesize Saharan dust, volcanic ash, topsoil, and rock quarry dust are potential sources of siliceous dust inhalation and SLM accumulations lacking chronic inflammation (silicosis); dust generation may be potentiated by road vehicle or wind suspension. Future investigations are warranted on the role of silicate inhalation and respiratory comorbidities in people, with monkeys, mongooses, or chickens serving as possible sentinels for exposure.

show abstract

Section: Discussionsupporting

confidence: 86%

Histology, prevalence, and environmental sources for pulmonary silicates depositions in domestic and wild animals

et al. 2023

View full text Add to dashboard Cite

show abstract

“…Recorded respiratory bacterial and viral pathogens of camels include Pasteurella haemolytica, Mycoplasma mycoides spp, Mycoplasma marginale and PPR virus (Paling et al 1978;Rufael 1996;Elfaki et al 2002;Abraham et al 2005). Apart from infectious agents, pneumoconiosis also causes chronic interstitial pneumonia and fibrosis (Hansen et al 1989), as was observed in this study. This study demonstrated pneumoconiosis to be a common environmental health hazard for camels.…”

Section: Discussionmentioning

confidence: 72%

Gross and microscopic pulmonary lesions of camels from Eastern Ethiopia

Bekele

2007

Trop Anim Health Prod

View full text Add to dashboard Cite

Camels are important animals for pastoralists in the northeastern, eastern, southeastern and southern parts of Ethiopia. This paper reports on abattoir study of respiratory lesions in 104 adult camels at the Dire Dawa abattoir (88 male and 16 female). The study showed 98% of the examined lungs had one or more lesions. The most common lesions were pulmonary fibrosis (50.00%), pneumoconiosis (34.62%), hydatid cyst (30.80%), pulmonary abscess (3.85%) and parasitic bronchopneumonia (0.96%). The distribution of pneumoconiosis and hydatid cyst varied significantly (p<0.05) among different lobes, the highest being seen in the caudal lobe. For the different lesions there was no significant (p>0.05) difference in distribution among male and female camels. Possible explanations for the occurrence of the lesions are discussed. And recommendations forecasted are made. Southern Ethiopia (Bekele 1999). Camel respiratory problem has received little consideration, even though it is an emerging disease in Ethiopia causing considerable loss of production and deaths (Rufael 1996; Bekele 1999). This paper reports a study of pulmonary lesions of 104 adult camels (88 male and 16 female) of unknown age and health status brought for slaughter to the Dire Dawa abattoir.

show abstract

“…In the previous reports of pneumoconiosis in camels, described pathologic features were similar to our results. Also, in a study by Hansen et al [21] chronic interstitial pneumonia and fibrosis were observed in the pneumoconiotic lungs.…”

Section: Goodarzi Azizi Koupaei Moshkelanimentioning

confidence: 83%

Tek Hörgüçlü Develerde (Camelus dromedarius) Anrako-silikozisin Akciğerlerdeki Patolojik Bulguları ve Pömoni Oluşumundaki Rolü

Goodarzi¹,

Azizi²,

Koupaei³

et al. 2014

Kafkas Univ Vet Fak Derg

View full text Add to dashboard Cite

Pneumoconiosis is an occupational lung disease which occurs by the accumulation of inhaled organic and inorganic particles in the pulmonary parenchyma. These particles interfere with the defense mechanisms of the lungs. This study was designed to describe the gross and histopathological features of pneumoconiosis in the lungs and its relation with occurrence of pneumonia in camels. 150 pneumonic and 100 healthy lungs were examined for pneumoconiosis in pathologic level. Macroscopic lesions of pneumoconiotic lungs were related to pneumonia and no remarkable features of pneumoconiosis were observed in the examined tissues. Pneumoconiosis was diagnosed in 43 out of 150 lungs with pneumonic lesions. Grossly healthy lungs did not show pneumoconiosis. Out of 43 pneumoconiotic lungs, 93% (n=40/43) were associated with interstitial pneumonia. Also, pneumoconiosis occurred in 2.32% (n=1/43) and 4.65% (n=2/43) of lungs with suppurative bronchopneumonia and bronchointerstitial pneumonia, respectively. Histopathologic findings related to pneumoconiosis were characterized by varying degrees of diffuse to nodular fibrosis as well as mild to heavy accumulations of mixed carbon and silicon dusts. Interlobular and interalveolar septa of alveoli were thickened by fibrosis and infiltration of mononuclear inflammatory cells. Crystalline silicon particles were in different shapes including filamentous, oblong and polygonal. Anthraco-silicosis particles were observed inside and outside of macrophages more adjacent to the vessels and bronchioles as well as lymphocytes infiltration. The color of particle aggregations was different from scant gray to brown or dense black, depending on the amount of silicon or carbon dust deposition. In the lungs, areas with prominent deposition of crystalline silica rather than carbon were gray to light brown and focal interstitial fibrosis was occurred. The present study suggests a positive causal relationship between pneumoconiosis and pneumonia. It seems these particles predispose animals to pulmonary diseases especially various type of pneumonia. Keywords: Pneumoconiosis, Pathology, Silicosis, Anthracosis, Camel Tek Hörgüçlü Develerde (Camelus dromedarius) Anrako-silikozisin Akciğerlerdeki Patolojik Bulguları ve Pömoni Oluşumundaki Rolü ÖzetPnömokoniozis pulmoner parankimde solunan organik ve inorganik partiküllerin birikmesi ile oluşan bir akciğer hastalığıdır. Bu partiküller akciğerlerin savunma mekanizmalarını bozarlar. Bu çalışma develerde pnömokoniozisin makroskopik ve histopatolojik özelliklerini tanımlamak ve pnömoni oluşumu ile ilişkisini ortaya koymak maksadıyla yapılmıştır. Çalışmada 150 pnömonili ve 100 sağlıklı akciğer pnömokoniozis yönünden incelendi. Pnömokoniotik akciğerlerdeki makroskopik lezyonlar pnömoni ile ilişkilendirildi ve incelenen dokularda pnömokoniozisin belirgin hiçbir özelliği gözlemlenmedi. Pnömoni lezyonlu 150 akciğerden 43'ünde pnömokoniozis tespit edildi. Makroskopik olarak sağlıklı akciğerlerde pnömokoniozis gözlemlenmedi. 43 adet pnömokonitik akciğerin %93'ü (n=40/...

show abstract

Silicate Pneumoconiosis in Camels (Camelus Dromedarius L.)

Cited by 13 publications

References 7 publications

Histology, prevalence, and environmental sources for pulmonary silicates depositions in domestic and wild animals

Histology, prevalence, and environmental sources for pulmonary silicates depositions in domestic and wild animals

Gross and microscopic pulmonary lesions of camels from Eastern Ethiopia

Tek Hörgüçlü Develerde (Camelus dromedarius) Anrako-silikozisin Akciğerlerdeki Patolojik Bulguları ve Pömoni Oluşumundaki Rolü

Contact Info

Product

Resources

About