Silica based Janus nanoparticles: Synthesis methods, characterization, and applications

Milian, Yanio E.; Claros, Martha; Ushak, Svetlana; Vallejos, Stella

doi:10.1016/j.apmt.2023.101901

Cited by 2 publications

(1 citation statement)

References 141 publications

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“…Additionally, emerging techniques like Janus nanoparticles and electrochemical deposition offer exciting possibilities. Janus nanoparticles, with distinct functionalities on opposing hemispheres, can be crafted using microfluidic techniques, enabling targeted interactions and controlled release properties [ 90 ]. Electrochemical deposition allows for the precise layer-by-layer assembly of functional molecules onto the silica nanoparticle surface, offering excellent control over surface chemistry and functionality [ 91 , 92 , 93 ].…”

Section: Synthesis and Functionalization Approaches For Silica-based ...mentioning

confidence: 99%

Nanoengineered Silica-Based Biomaterials for Regenerative Medicine

Abdelhamid,

Khalifa,

et al. 2024

IJMS

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The paradigm of regenerative medicine is undergoing a transformative shift with the emergence of nanoengineered silica-based biomaterials. Their unique confluence of biocompatibility, precisely tunable porosity, and the ability to modulate cellular behavior at the molecular level makes them highly desirable for diverse tissue repair and regeneration applications. Advancements in nanoengineered silica synthesis and functionalization techniques have yielded a new generation of versatile biomaterials with tailored functionalities for targeted drug delivery, biomimetic scaffolds, and integration with stem cell therapy. These functionalities hold the potential to optimize therapeutic efficacy, promote enhanced regeneration, and modulate stem cell behavior for improved regenerative outcomes. Furthermore, the unique properties of silica facilitate non-invasive diagnostics and treatment monitoring through advanced biomedical imaging techniques, enabling a more holistic approach to regenerative medicine. This review comprehensively examines the utilization of nanoengineered silica biomaterials for diverse applications in regenerative medicine. By critically appraising the fabrication and design strategies that govern engineered silica biomaterials, this review underscores their groundbreaking potential to bridge the gap between the vision of regenerative medicine and clinical reality.

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