Silent Peptic Ulcer Disease Perforation

Causes of Acute Peritonitis and its Outcome in Tertiary Medical Centre

“…Early surgical intervention have decreased the mortality, if eradication of H. pylori by triple therapy and make early diagnosis of typhoid and treat it with appropriate antibiotics then peritonitis can be significantly prevented, so early treatment of these diseases and use of boiled water by community can reduce incidence of peritonitis due to typhoid and H. pylori infection peptic ulcer perforation. Duodenal perforation is mainly due to H. Pylori (77%) 5 and occurred commonly in low socioeconomic group who cannot buy mineral water, But low socioeconomic group can use boiled water to prevent perforation leading to peritonitis and physicians must diagnose early and properly treat H. pylori infections. Typhoid fever in our study was the leading cause of perforation of gut (28.70%) as compared to studies conducted by Garg RK 2016 9 , Bali RS 2014 10 and Khana AK 1984 11 where peptic ulcer was leading cause, most probably reason is unhygienic conditions and use of contaminated water.…”