Silent MRI infarcts and the risk of future stroke

Abstract

The presence of silent cerebral infarcts on MRI is an independent predictor of the risk of symptomatic stroke over a 4-year follow- up in older individuals without a clinical history of stroke.

Cognitive Impairment in the Aging Dialysis and Chronic Kidney Disease Populations: An Occult Burden

“…Among CKD patients, the prevalence of silent infarcts is inversely reported to kidney function as measured by cystatin C in the Cardiovascular Health Study (38); among hemodialysis patients in another study, the prevalence was 49 percent, or 5 times more common than in control subjects (39). Silent strokes are associated with increased risk of subsequent clinically evident stroke, cognitive and physical decline, and incident dementia (36,37,40) in both the general and CKD/dialysis populations (39,41).…”

Associations of Brachial-Ankle Pulse Wave Velocity and Carotid Atherosclerotic Lesions with Silent Cerebral Lesions

“…Compared with symptomatic cardiovascular disorders such as stroke and coronary heart diseases, SCI and intracranial stenosis have been understudied in terms of their risks and consequences. Some studies showed SCI was associated with future stroke (14)(15)(16)(17)(18). However, the relationships among SCI, intracranial stenosis, carotid plaque, IMT, and baPWV are scarcely known.…”

Do Silent Brain Infarctions Predict the Development of Dementia After First Ischemic Stroke?

“…A lot of studies showed a relationship between dementia occurrence and volume or strategic location of infarction, a host of cranial CT and MRI [14]. These studies provide evidence that dementia related to stroke is associated with higher mean tissue loss, infarct number, location (eg, dominant thalamus and angular gyrus, bilateral infarcts, deep frontal infarcts, left hemisphere infarcts), and degree of "cerebral atrophy" as demonstated by ventricular size, area of subarachnoid space, and size of the third ventricle.…”