SIKLOHEKZANDIKARBOKSILLI ASIDIN SENTEZI VE pH ETKISI İLE SU VE ORGANIK FAZLARDAN EKSTRAKSIYONUNUN İNCELENMESI

Abstract

In this study, iron cyclohexanedicarboxylic acid was synthesized under refluxing conditions. The structural characterization of the complex was performed by using physico-chemical and spectroscopic methods. The effect of pH on division constant () and extraction percentages (% E) in water and organic phase was investigated with the extraction method. At the end of the experiment, most of the Fe 2+ ions in the water phase at pH=7.5 passed into the organic phase. Above this pH, the extraction percentage decreased because of the transition from water phase to organic phase. Iron cyclohexanedicarboxylic acid was extracted with ether, petroleum ether, benzole and carbon tetrachloride from aqueous solution and microbial activities of the complex were studied. The activity data showed that iron cyclohexanedicarboxylic acid has an important antibacterial and antifungal activities.

Synthesis of macrocyclization cyclophanes and their metal complexes, characterization and antimicrobial activity

“…Compared to the sulfamethoxazole drug, it has much low-er antimicrobial activities. Complex six is effective against bacteria and fungal even though the stated absorbance measurements have some statistical flaws [25,26]. The absorbance values were added for informational purposes even though the other synthetic compounds 3, 5, and 7 did not exhibit the anticipated inhibitory effects on the target bacteria (Fig.…”