2007
DOI: 10.1001/archderm.143.6.815-b
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Signs of a “Broken Heart”: Suspected Muehrcke Lines After Cardiac Surgery

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Cited by 8 publications
(2 citation statements)
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“…[ 1 ] Muehrcke’s lines accompany severely low serum albumin,[ 23 ] probably resulting from vascular compression within the nail bed because of local edema. They have also been associated with multiple etiologies including nephrotic syndrome, liver cirrhosis, severe malnutrition, anticancer therapy,[ 24 ] severe cachexia in AIDS,[ 25 ] Cushing’s syndrome,[ 26 ] and even in patients with transient hypoalbuminemia,[ 27 ] or normoalbuminemia. [ 28 ] They were seen in many of our patients, both with normal and reduced serum proteins.…”
Section: Discussionmentioning
confidence: 99%
“…[ 1 ] Muehrcke’s lines accompany severely low serum albumin,[ 23 ] probably resulting from vascular compression within the nail bed because of local edema. They have also been associated with multiple etiologies including nephrotic syndrome, liver cirrhosis, severe malnutrition, anticancer therapy,[ 24 ] severe cachexia in AIDS,[ 25 ] Cushing’s syndrome,[ 26 ] and even in patients with transient hypoalbuminemia,[ 27 ] or normoalbuminemia. [ 28 ] They were seen in many of our patients, both with normal and reduced serum proteins.…”
Section: Discussionmentioning
confidence: 99%
“…8 ). Initially described in 1956 by their namesake Dr. Robert Muehrcke in patients with severe and long-standing hypoalbuminemia (< 2.2 g/100 mL) [ 82 ], currently they are considered indicative of a range of systemic pathologies without hypoalbuminemia, including kidney disease, rheumatoid arthritis, heart transplant [ 86 , 87 ], and after placement of a left ventricular assist device [ 88 ]. Systemic retinoids and various cytostatic regimens have also been observed to cause them.…”
Section: Clinical Presentationsmentioning
confidence: 99%