Significant association between the progression of coronary artery calcification and dyslipidemia in patients on chronic hemodialysis

Thirty-Month Follow-Up of Coronary Artery Calcification in Hemodialysis Patients: Different Roles for Inflammation and Abnormal Calcium-Phosphorous Metabolism?

“…In some cases, and for different periods of time, aluminum-containing phosphate binders were used. Lipid profile, a traditional risk factor for cardiovascular events, was not correlated with DCAC, which opposes the results of a study by Tamashiro et al [10] but is in agreement with other studies. [12,15] Age and duration of HD therapy were not correlated with DCAC as well.…”

“…This continuous CAC progression is in accordance with the findings of previous studies. [5,6,[10][11][12][13][14][15][16][17] CAC progression (DCAC) was not affected by a history of hypertension. Univariate analysis revealed that DCAC was not correlated with the amount of essential calcium intake administered as calcium bicarbonate during the study period, which is in disagreement with the results of other studies.…”

“…Age, dialysis duration, lipid profile, hypertension, abnormal calciumphosphorous metabolism, the amount of elemental calcium intake administered as calcium carbonate, and inflammation all have been associated in different studies with CAC progression in HD patients. [5,6,[10][11][12][13][14][15][16][17] The aim of the present study was to evaluate the significance of all of the above factors in CAC score progression during a 30-month period in HD patients. CAC score was assessed by repeating every six months conventional computed tomography (CCT).…”

Coronary Artery Calcification, ADMA, and Insulin Resistance in CKD Patients

“…C oronary artery calcification (CAC) is regarded as an index of the severity of atherosclerotic vascular disease and may predict future adverse cardiovascular events in patients on dialysis (1)(2)(3). In patients with chronic kidney disease (CKD) before initiation of renal replacement therapy, CAC is already present in the early phase of CKD (4 -6) and among diabetic nephropathy (7).…”

Long-Term Effect of Different Dialysate Calcium Concentrations on Parathyroid Hormone Levels in Hemodialysis Patients

“…[21,22] Other risk factors include history of coronary artery disease, diabetes, dyslipidemia, old age, and an elevated Ca×P product. [23,24] More than half of patients in all patients in this study died from cardiovascular reasons, and there was no difference in cumulative survival between groups. An association between high D [Ca] and all-cause mortality noted in DOPPS study [25] was not found in our study.…”