Significance of Signs and Symptoms in Benign Prostatic Hypertrophy

Castro, J. E.; Griffiths, H. J. L.; Shackman, Ralph

doi:10.1136/bmj.2.5657.598

Cited by 77 publications

(18 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Instead, LUTS symptom severity was found to be only significantly correlated with lower overall health status which interestingly, has also been associated with decreased testosterone levels in multiple studies (57-60). A lack of correlation between prostatic volume and LUTS symptom severity was also seen in a study of 45 men by Castro et al In this study, prostatic size was correlated with an increase in urethral resistance during micturition, but this did not result in worsening of symptoms (61). In contrast to these studies is a secondary analysis of the Medical Therapy of Prostatic Symptoms (MTOPS) study, in which Crawford et al found that men with a prostate volume of >31 mL had a higher risk of BPH progression than men with prostates <30 mL (62).…”

Section: Luts/bph and Trtsupporting

confidence: 65%

Testosterone replacement therapy and voiding dysfunction

Baas

Köhler

2016

Transl. Androl. Urol.

View full text Add to dashboard Cite

Testosterone replacement therapy (TRT) represents an increasing popular treatment option for men with late-onset hypogonadism (LOH). Because of unsubstantiated beliefs of testosterone’s effect on the prostate, the FDA has recently placed a warning on testosterone products, stating that TRT may worsen benign prostatic hyperplasia (BPH). Within this review article we have demonstrated the current understanding of the physiology of testosterone and its relationship with prostatic and lower urinary tract physiology. The current evidence suggests that not only does TRT not worsen lower urinary tract symptoms (LUTS), but that hypogonadism itself is an important risk factor for LUTS/BPH.

show abstract

Section: Luts/bph and Trtsupporting

confidence: 65%

Testosterone replacement therapy and voiding dysfunction

Baas

Köhler

2016

Transl. Androl. Urol.

View full text Add to dashboard Cite

show abstract

“…Castro et al [9] have suggested a direct relation be tween prostatic size and the degree of urodynamic ob struction. Likewise, Andersen and Nordling [10] found that the estimated prostatic weight at cystoscopy corre lated well to urodynamic parameters of bladder outlet obstruction, such as maximum flow rate, opening pres sure and minimum urethral resistance.…”

Section: Introductionmentioning

confidence: 99%

Significance of Prostatic Weight in Prostatism

et al. 1983

View full text Add to dashboard Cite

In addition to routine evaluation, 68 patients with prostatism underwent blinded urodynamic testing prior to transurethral prostatectomy and were reexamined symptomatologically and urodynamically at 3 and 12 months after surgery to determine if prostatic weight could predict postoperative outcome. Resected prostatic weight correlated with estimated weight at cystoscopy and with obstructive symptoms, but not with urodynamic variables of infravesical obstruction. Patients with small prostates improved symptomatologically to the same degree as patients with larger glands, although they did not improve to the same degree urodynamically. Prostatic weight, therefore, could not be used to predict the outcome of transurethral surgery.

show abstract

“…The symptom complex of slow stream, hesitancy, frequency, nocturia, urgency, urge incontinence and post-micturition dribble in the older male patient is often attributed to benign prostatic hypertrophy. The significance of these symptoms in the older male patient has been doubted (Castro et al, 1969), although it has been suggested that certain of these symptoms, namely frequency, nocturia and urgency, may be associated with bladder instability (Turner Warwick et al, 1973).…”

Section: Introductionmentioning

confidence: 99%

The Significance of the Symptoms Associated with Bladder Outflow Obstruction

Abrams¹,

Feneley²

1978

Urol Int

153

View full text Add to dashboard Cite

The symptomatology and urodynamic findings of 318 male patients (45–84 years) with suspected bladder outflow obstruction have been analysed. Inflow cystometry showed that 57% of patients had unstable bladders and a pressure flow analysis of micturition that 67% had obstructed micturition. The symptoms of urgency, urge incontinence and frequency were associated with bladder instability and not with obstruction. The symptoms of hesitancy and slow stream were significantly related to obstruction. Post-micturition dribble and nocturia were related to neither urodynamic finding in this series.

show abstract

Significance of Signs and Symptoms in Benign Prostatic Hypertrophy

Cited by 77 publications

References 6 publications

Testosterone replacement therapy and voiding dysfunction

Testosterone replacement therapy and voiding dysfunction

Significance of Prostatic Weight in Prostatism

The Significance of the Symptoms Associated with Bladder Outflow Obstruction

Contact Info

Product

Resources

About