1973
DOI: 10.1136/bmj.3.5872.128
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Significance of Hyperamylasaemia and Abdominal Pain in Diabetic Ketoacidosis

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1973
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Cited by 51 publications
(21 citation statements)
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“…[1][2][3][4] However, the incidence of acute pancreatitis in DKA seems to be higher in adults compared with children and is reported to be more than 10%. 5 We also have found that pancreatic enzyme elevations occur much less commonly in the setting of new-onset diabetes without DKA.…”
Section: Discussionmentioning
confidence: 99%
“…[1][2][3][4] However, the incidence of acute pancreatitis in DKA seems to be higher in adults compared with children and is reported to be more than 10%. 5 We also have found that pancreatic enzyme elevations occur much less commonly in the setting of new-onset diabetes without DKA.…”
Section: Discussionmentioning
confidence: 99%
“…In an earlier study we concluded that the pancreas was the most likely source of the hyperamylasemia commonly encountered in diabetic ketoacidosis, even though abdominal pain and other clinical stigmata of pancreatitis occurred in such patients no more frequently than in patients with normal serum amylase levels. 18 Neither the degree of initial hyperglycemia or acidosis nor the speed of onset of the metabolic decompensation bore any relationship to the incidence of enzyme abnormalities. Since some of the isolated enzyme abnormalities, especially those concerning ADase activity, occurred at or soon after admission, dehydration was examined as a possible contributing factor.…”
Section: Discussionmentioning
confidence: 98%
“…Though even grossly raised serum amylase levels may not in themselves be associated with increased mortality or morbidity (Knight et al, 1973) all patients with accidental hypothermia and hypothermic myxoedema should have their serum amylase and blood glucose levels measured soon after admission to hospital. Not only will this indicate diabetic ketoacidosis when it is present but raised amylase levels will identify patients likely to develop diabetic ketoacidosis in the ensuing few days.…”
Section: Discuss'ionmentioning
confidence: 99%