Significance of gram-resistant flora in etiology of nosocomial infections in determining rational antibiotic therapy

Abstract

In recent years, the problem of resistance of gram-negative microorganisms to carbapenems, as well as the emergence of multiresistant strains is gaining urgency. This problem is of particular importance in neonatal practice due to the age limitations of the use of many antibiotics and the lack of specific recommendations. Local bacteriological monitoring data should be taken into account when selecting a starting antibiotic, and for this purpose, methods of rapid identification of the pathogen and its resistance mechanisms should be introduced. Pediatricians need controlled trials of new antibiotics to successfully treat MDR-Gram-infections.