Significance of Estrogenic Factor in Tumors and Tissues of the Human Female

Lack of Estrin Concentration in Adenofibroma of the Mammary Gland in Rats

“…Since, however, the amount and source of the mammary tissue were not given, this comparison is without value. Doubt as to the presence of actual concentration of hormone in these tumors was voiced by Frank et al ( 6 ) , who found similar amounts of estrin in normal uterus and psoas muscle (800-8000 rat units per kilo). No confirmation of Geschickter and Lewis' findings has yet appeared except for the finding by Heiman and Krehbiel ( 7 ) of 1 rat unit per gram fresh weight of a rat adenofibroma.…”