Significance of acute multiple infarcts in multiple cerebral circulations on initial diffusion weighted imaging in stroke patients

Acute cerebral infarcts in multiple arterial territories associated with cardioembolism

“…We found acute cerebral infarcts in more than one arterial territory in 8.8% of the patients. This is similar to two recent studies (9.8 and 9.7%) . Other studies have reported higher frequencies, but different inclusion criteria make the comparison difficult .…”

“…This is similar to two recent studies (9.8 and 9.7%) . Other studies have reported higher frequencies, but different inclusion criteria make the comparison difficult . Many studies have included patients with several DWI lesions in the same arterial territory.…”

“…. However, the number of DWI‐based studies supporting this concept is surprisingly low, and previous results are conflicting . Furthermore, most studies have used different methods and have been retrospective with too small sample sizes .…”

From clinical to tissue-based dual TIA

“…25 Cardioembolic etiology can cause repeated ischemic events and increase future stroke risk. Considering the intention of repeated tissue-defined ischemic attacks, we adopted a relatively strict definition of different arterial territories (among the 2 carotid/anterior and one vertebrobasilar/posterior circulations).…”

Ischemic lesions in all territories as a marker of malignant hypercoagulability

“…The finding of a negative transthoracic echocardiography in these cases argues for a hypercoagulable cause for stroke. Differential diagnosis with this pattern can be stroke of cardiac origin (eg, atrial fibrillation), hematological diseases, and vasculitis …”