Abstract:RAS and RHO proteins constitute two branches of the RAS superfamily of small guanosine triphosphatases (GTPases) (Figure 1). Like all GTPases, these proteins cycle between an active, guanosine triphosphate (GTP)‐bound form, and an inactive, guanosine diphosphate (GDP)‐bound form. Two families of proteins, guanine nucleotide exchange factors (GEFs) and GTPase activating proteins (GAPs), activate and inactivate the GTPases, respectively, and the activity of GEFs and GAPs are controlled by a large number of cellu… Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.