Abstract:Sodium appetite is an innate behavior occurring in response to sodium depletion that induces homeostatic responses such as the secretion of the mineralocorticoid hormone aldosterone from the zona glomerulosa of the adrenal cortex and the stimulation of the peptide hormone angiotensin II (ANG II). The synergistic action of these hormones signals to the brain the sodium appetite that represents the increased palatability for salt intake. This narrative review summarizes the main data dealing with the role of min… Show more
“…It is also a neural transmitter. In the brain stem, diencephalon and limbic system neural circuits controlling salt and water balance even behavior elements containing Ang II-releasing neurons [5,6]. These complex actions are very far from the original epithelial salt-conserving function of this archaic agonist.…”
Section: Pleiotropic Effects Of Ang IImentioning
confidence: 99%
“…Several mammals have a salt appetite, and humans are among them. A salt appetite might have had an additional advantage in early humans turning hunters: even unsalted meat has a fairly salty taste [5,6].…”
Section: Salt Appetite Salt Preference and The Overconsumption Of Saltmentioning
Angiotensin II (Ang II) is a hormone with much more complex actions than is typical for other agonists with heterotrimeric G protein-coupled receptors (GPCRs) [...]
“…It is also a neural transmitter. In the brain stem, diencephalon and limbic system neural circuits controlling salt and water balance even behavior elements containing Ang II-releasing neurons [5,6]. These complex actions are very far from the original epithelial salt-conserving function of this archaic agonist.…”
Section: Pleiotropic Effects Of Ang IImentioning
confidence: 99%
“…Several mammals have a salt appetite, and humans are among them. A salt appetite might have had an additional advantage in early humans turning hunters: even unsalted meat has a fairly salty taste [5,6].…”
Section: Salt Appetite Salt Preference and The Overconsumption Of Saltmentioning
Angiotensin II (Ang II) is a hormone with much more complex actions than is typical for other agonists with heterotrimeric G protein-coupled receptors (GPCRs) [...]
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