2003
DOI: 10.1074/jbc.m302747200 View full text |Buy / Rent full text
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Abstract: In retinal rod photoreceptor cells, transducin (G t ) and cyclic GMP phosphodiesterase (PDE) are peripherally anchored to the cytoplasmic surface of the disk saccules. We have examined the role of specific phospholipids in the interaction of these proteins with native osmotically intact disk vesicles, employing spin-labeled phospholipid analogues (2% of total phospholipids) and bovine serum albumin back-exchange assay. Inactive GDPbound transducin exclusively reduced the extraction of negatively charged phosph… Show more

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