Signal processing and uncertainty in an isothermal titration calorimeter

Heats of Mixing Using an Isothermal Titration Calorimeter: Associated Thermal Effects

“…Finally, an average value (K = 391 ± 9 mV/W) was obtained from different working conditions. A comparison between our experimental results and those recommended in the literature, has been reported elsewhere [ 11 ].…”

“…t 1 and t 2 are the moments in which the signal y 1 ( t ) is at the initial and final experimental zeroes of the calorimetric signal. K is the calorimetric sensitivity (in this case, K =391 mV/W [ 11 ]) obtained from chemical calibrations.…”

“…In short, the electrical and chemical calibrations lead to slightly different values for the sensitivity. This is the reason why it is necessary to carry out a chemical calibration, as described in a previous work [ 11 ]. Two binary systems (ethanol + water [ 12 ] and cyclohexane + benzene [ 13 ]) were used for the chemical calibration.…”

Study of the stirring effect in a TAM2277-205 isothermal Titration Calorimeter

“…The calorimetric signal is read directly by a digital multimeter HP3457A (±10 nV). The calibration of the calorimeter has already been described in a previous paper [4] and the obtained sensitivity was 391±9 mV W -1 . For the mentioned calibration, the following liquids systems were used: water+ethanol and cyclohexane+ benzene.…”

“…This way to use it is classical and very widespread [1]. (ii) A second way of using the ITC consists in 'the continuous injection' of a liquid on other at a very low velocity and, after processing the calorimetric signal, it is determined the power that is developed in the mixture process in terms of the concentration [2][3][4]. This way of ITC operation is not very used due to the difficulty in the mathematical treatment of the calorimetric signal; however, it provides a more detailed thermodynamical information of the thermal process under study.…”