Abstract:WhiB1 belongs to the WhiB‐like family that is widely distributed in the phylum of Actinobacteria. It is a monomeric transcription factor that contains a [4Fe–4S] cluster in the holo‐form. In mycobacteria, the holo‐WhiB1 interacts with the domain 4 of the σ
70
‐family primary sigma factor (σ
A
4
) in the RNA polymerase holoenzyme and plays an essential role in active cell growth. Domain 4 of the σ
70
‐family primary sigma factor… Show more
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