Siderotic cataract with no signs of intraocular foreign body

Abstract

BackgroundOcular siderosis is a clinical condition induced by deposition of an iron-containing intraocular foreign body. We report a unique case of histopathologically proven lens siderosis in a young woman with a preceding history of trauma but no signs of retained intraocular foreign body.Case presentationA 32-year-old woman presented with an opacified lens showing brownish deposits on the anterior capsule and underwent cataract surgery. Preoperative ophthalmic examination did not show any retained intraocular foreign body. Histopathologic staining of the anterior capsule confirmed the presence of iron deposits and macrophages. Electroretinography examination performed in the postoperative period showed the changes characteristic of retinal degeneration in ocular siderosis.ConclusionThis case illustrates the importance of close monitoring of patients with a history of trauma or previous penetrating injury to the eye, even if there is no intraocular foreign body, because they might develop ocular siderosis at a later stage. This case report underscores the importance of electroretinography and histopathologic analysis, in addition to ophthalmic examination, in the diagnosis of ocular siderosis.Electronic supplementary materialThe online version of this article (doi:10.1186/s12886-017-0424-4) contains supplementary material, which is available to authorized users.

Siderotic glaucoma without detectable intraocular foreign body in a pseudophakic eye: a case report

“…In our case, no distinct iris atrophy was found, but the heterochromia was remarkable. Moreover, similar to previous studies, a special Prussian blue staining in our patient showed scattered iron deposition in the TM [ 20 ]. Electrophysiology also revealed typical amplitude loss on ERG.…”

Ocular siderosis: a misdiagnosed cause of visual loss due to ferrous intraocular foreign bodies—epidemiology, pathogenesis, clinical signs, imaging and available treatment options

“…Moreover, brownish or rusty spots can develop on the anterior lens capsule due to iron deposition in epithelial cells, and sometimes, the lens itself could appear yellowish with cataract development [ 39 ]. The last phenomenon can also be due to penetrating trauma [ 40 , 41 ].…”

Efficiency of different imaging methods in detecting ocular foreign bodies

“…[3][4][5] A particularly high incidence of OFB-associated injuries has been reported in China. 6 These injuries and their high potential for serious complications (including cataract, 7,8 inflammation, 9 glaucoma, 7 and ocular siderosis 6,10 ) are a major risk factor for vision disorders, even with the most recent advances in surgical techniques and equipment. 3,6,11 The first step in the clinical management of OFBs is the detection and localization of these particles, followed by surgical removal.…”