This presentation assesses the role of liver transplantation in treating end-stage liver disease today. Most of the unresolved issues in human liver transplantation have been developed in two major series, the one from Denver and the other from the combined Cambridge/Kings College Hospital effort in England. The findings of these groups are highlighted, as are the changes in technique that have led to considerably improved survival in the past 2 years.
THE CURRENT STATUS OF HUMAN LIVER TRANSPLANTATIONHuman liver transplantation has developed frustratingly slowly since the first liver graft in man was performed in Denver in March 1963. However, the success rate has improved remarkably in the last 2 years and the procedure has at last moved out of the developmental and experimental phase and become a truly therapeutic procedure in Denver.