Sicca-Symptomatik und Hörverlust beim Behçet-Syndrom

Eichhorn, Andreas; Kirch, Wilhelm

doi:10.1055/s-2007-1024035

Cited by 7 publications

(2 citation statements)

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“…Other less frequently associated diseases include systemic lupus erythematosus, polyarteritis nodosa, Reiter’s syndrome, psoriatic arthritis, giant cell arteritis and Cogan syndrome 1 , 4 – 7 ) . The scleritis occurred in patients with BD has been rarely reported in the literature 1 , 8 ) . We describe a female patient who developed the scleritis in the course of BD.…”

Section: Introductionmentioning

confidence: 99%

A Case of Nodular Scleritis in Association With Behcet`s Disease

Chang

Cho

2001

Korean J Intern Med

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Approximately 50 % of patients with scleritis are known to be associated with systemic connective tissue diseases or vasculitic diseases such as rheumatoid arthritis (RA), Wegener’s granulomatosis, relapsing polychondritis, and systemic lupus erythematosus. The patients with scleritis in association with Behcet’s disease (BD) have been rarely described in the literature. We report a 46-year-old female patient with BD who developed the nodular scleritis.

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Section: Introductionmentioning

confidence: 99%

A Case of Nodular Scleritis in Association With Behcet`s Disease

Chang

Cho

2001

Korean J Intern Med

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“…This concept was introduced by Lehnhardt 8 and is supported by the fact that hearing loss is associated with different autoimmune diseases such as Cogan syndrome, rheumatoid arthritis, 9 Sjögren syndrome, 10 and Behçet's disease. 11 Hisashi et al 12 were the first to demonstrate an association between progressive sensorineural hearing loss in patients with lupus erythematodes and antiphospholipid antibodies. They proposed that in patients with lupus erythematodes these antibodies are causative for thrombosis of the labyrinth leading to progressive sensorineural hearing loss.…”

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confidence: 99%

Coincidence of normal tension glaucoma, progressive sensorineural hearing loss, and elevated antiphosphatidylserine antibodies

Kremmer

Kreuzfelder²,

Bachor³

et al. 2004

British Journal of Ophthalmology

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Background: Recently, in patients with normal tension glaucoma (NTG) elevated levels of antiphosphatidylserine antibodies (APSA), a subgroup of antiphospholipid antibodies (APLA) were found. Progressive sensorineural hearing loss (PSHL) is associated with autoimmune diseases and also the presence of APLA. Methods: To investigate a possible association between NTG and PSHL, 34 patients (age range 31-81 years) with NTG were evaluated for evidence of audiovestibular disorders. Besides ophthalmological standard examinations (slit lamp, IOP, funduscopy, perimetry) scanning laser tomography and polarimetry were performed. From all patients' audiograms, stapedial thresholds and otoacoustic emissions were obtained. The serological testing of patients and controls (40 healthy blood donors older than 50 years) concerned IgG and IgM levels of antibodies against phosphatidylserine (APSA) and b2 glycoprotein. Results: 23 of 34 NTG patients had hearing loss (PSHL n = 11; presbyacusis n = 12). The NTG patients had significantly higher APSA levels than controls. Elevated APSA concentrations were significantly more frequent in patients with NTG and hearing loss compared with NTG patients with normacusis. Conclusions: These findings show that NTG and hearing loss have a high coincidence. The elevated APSA levels may indicate an association with similar systemic autoimmune processes.

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