Shunt in critically ill Covid-19 ARDS patients: Prevalence and impact on outcome (cross-sectional study)

Trifi, Ahlem; Ouhibi, Asma; Mahdi, Asma; Masseoud, Linda; Seghir, Eya; Meftah, Amal; Sellaouti, Salim; Abdennebi, Cyrine; Daly, Foued; Touil, Yosr; Abdellatif, Sami; Lakhal, S. Ben

doi:10.1016/j.jcrc.2022.154048

Cited by 3 publications

(2 citation statements)

References 6 publications

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“…Physiologically, the presence of such shunts is suggested by the appearance of microbubbles in the systemic circulation based on transcranial Doppler imaging 37 and in up to 16% of patients on echocardiography. 38 They have also been demonstrated radiographically at the level of the secondary pulmonary lobule on CT reconstructions, 39 and on autopsy in severe COVID-19 lung disease. 40 However, it should be noted that the presence of such shunts has been reported in a subset of non-COVID ARDS undergoing echocardiography, suggesting that this process is likely not unique to COVID-19 lung injury.…”

Section: Introductionmentioning

confidence: 95%

Pathophysiology of Hypoxemia in COVID-19 Lung Disease

Swenson

Hardin

2023

Clinics in Chest Medicine

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Section: Introductionmentioning

confidence: 95%

Pathophysiology of Hypoxemia in COVID-19 Lung Disease

Swenson

Hardin

2023

Clinics in Chest Medicine

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“…These comorbidities, combined with COVID-19 infection, create a complex clinical contributor to the patient's respiratory distress. The etiology and significance of this shunt in the context of COVID-19 infection require further investigation [ 7 , 8 ].…”

Section: Discussionmentioning

confidence: 99%

Right-to-Left Intra-cardiac Shunt in a COVID-19 Patient Leading to Stroke and Poor Prognosis: A Case Report and Review of the Literature

Damlakhy,

Barham,

Omar

et al. 2024

Cureus

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Coronavirus disease 2019 (COVID-19) often presents with a wide range of complications, including respiratory distress, acute respiratory distress syndrome (ARDS), and hypercoagulable states with resultant cerebrovascular incidents. Intra- and extra-pulmonological shunts can further complicate patient courses, leading to persistent hypoxemia and paradoxical emboli, resulting in potentially life-threatening consequences, necessitating a comprehensive, multidisciplinary approach to patient care. Here we present the case of a 73-year-old male who experienced severe persistent hypoxemic respiratory failure, superimposed methicillin-resistant Staphylococcus aureus (MRSA) pneumonia, and stroke with a previously undiagnosed patent foramen ovale (PFO) contributing to his clinical presentation.

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