Should the diagnosis of late paraphrenia be abandoned?

Almeida, Osvaldo P.; Howard, Robert; Förstl, Hans; Levy, Raymond

doi:10.1017/s0033291700032670

Cited by 25 publications

(11 citation statements)

References 23 publications

(38 reference statements)

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“…used late paraphrenia as a descriptive term for patients who developed a predominantly paranoid psychosis late in life, in whom signs of sustained confusion or dementia were not present and in whom symptoms were not due to an affective disorder. Late paraphrenia was never intended to be synonymous with late-onset schizophrenia, and we have argued elsewhere (Almeida et al, 1992) that it is probably incorrect to equate the two conditions. Some authors have, however, considered that they are the same entity (Fish, 1960;Grahame, 1984), while others have seen late paraphrenia as a spectrum of disorders characterized by paranoid delusions (Post, 1966;Holden, 1987).…”

mentioning

confidence: 99%

Permeable walls, floors, ceilings and doors. Partition delusions in late paraphrenia

Howard

Castle

O’Brien

et al. 1992

Int J Geriat Psychiatry

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SUMMARYA partition delusion is the belief that people, objects or radiation can pass through what would normally constitute a barrier to such passage. These delusions have been reported to be common in late paraphrenia and late-onset schizophrenia. Such partition delusions were found in 68% of 50 patients with late paraphrenia, but only in 13% of patients with schizophrenia who had grown old and in 20% of young schizophrenics. Partition delusions, often in association with persecutory beliefs, are common in late paraphrenia and we discuss some possible reasons €or this.

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confidence: 99%

Permeable walls, floors, ceilings and doors. Partition delusions in late paraphrenia

Howard

Castle

O’Brien

et al. 1992

Int J Geriat Psychiatry

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“…His premorbid social function was almost normal, and the results of cognitive function tests performed after his psychiatric symptoms improved showed that he did not have remarkable neurocognitive impairment. He had sensory de cit, which is common in late paraphrenia [9], and developed psychotic symptoms after 60 years of age without any history of psychiatric disorders. This suggested that his catatonia occurred because of late paraphrenia, which is classi ed as very-late-onset schizophrenia-like psychosis, and has been recognized to be independent of schizophrenia [10].…”

Section: Discussionmentioning

confidence: 99%

Catatonia Associated With Late Paraphrenia Successfully Treated With Lithium: A Case Report

Sugawara¹,

Takamatsu²,

Hashimoto³

et al. 2020

Preprint

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Background: Catatonia is a psychomotor syndrome that presents various symptoms ranging from stupor to agitation, with prominent disturbances of volition. Its pathogenesis is poorly understood. Benzodiazepines and electroconvulsive therapy (ECT) are safe and effective standard treatments for catatonia; however, alternative treatment strategies have not been established in cases where these treatments are either ineffective or unavailable. Here, we report a case of catatonia associated with late paraphrenia classified as very-late-onset schizophrenia-like psychosis, which was successfully treated with lithium. Case presentation: A 66-year-old single man with hearing impairment developed hallucination and delusions and presented with catatonic stupor after a fall. He initially responded to benzodiazepine therapy; however, his psychotic symptoms became clinically evident and benzodiazepine provided limited efficacy. Blonanserin was ineffective, and ECT was unavailable. His catatonic and psychotic symptoms were finally relieved by lithium monotherapy.Conclusions: Catatonic symptoms are common in patients with mood disorders, suggesting that lithium may be effective in these cases. Moreover, lithium may be effective for both catatonic and psychotic symptoms, as it normalizes imbalances of excitatory and inhibitory systems in the brain, which underlies major psychosis. Cumulative evidence from further cases is needed to validate our findings.

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“…The nosological status of psychotic illnesses in late life psychoses remains debatable, with the relationship between paraphrenia and late onset schizophrenia not yet resolved (Almeida et al, 1992). The patient described above has chronic schizophrenia meeting DSM-III-R criteria.…”

Section: Discussionmentioning

confidence: 99%

The use of clozapine in older people

Ball

1992

Int J Geriat Psychiatry

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Should the diagnosis of late paraphrenia be abandoned?

Cited by 25 publications

References 23 publications

Permeable walls, floors, ceilings and doors. Partition delusions in late paraphrenia

Permeable walls, floors, ceilings and doors. Partition delusions in late paraphrenia

Catatonia Associated With Late Paraphrenia Successfully Treated With Lithium: A Case Report

The use of clozapine in older people

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