Should neuromuscular blocking agents always be used for tracheal intubation? Reply to Br J Anaesth 2018; 122: e8–9

Hunter, Jennifer M.

doi:10.1016/j.bja.2018.09.012

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Chronic Administration Of Relaxants1

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2019

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“…During long administration, cases have been reported of development of resistance to pancuronium, vecuronium and atracurium 101 . This is related to increased extrajunctional sensitivity to acetylcholine and/or receptor up‐regulation as a result of long neuromuscular blockade 102,103 …”

Section: Chronic Administration Of Relaxantsmentioning

confidence: 99%

Skeletal Muscle Relaxants: Pharmacodynamics and Pharmacokinetics in Different Patient Groups

Booij

Vree

2000

Int J Clinical Practice

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SUMMARYMuscle relaxants can be safely administered during anaesthesia, providing the basic pharmacodynamic and pharmacokinetic characteristics of the compounds together with the physiological status of the patient are known. In this review the pharmacodynamics and pharmacokinetics of the neuromuscular blocking agents are discussed and related to the physical health or disease state of groups of patients.

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Section: Chronic Administration Of Relaxantsmentioning

confidence: 99%

Skeletal Muscle Relaxants: Pharmacodynamics and Pharmacokinetics in Different Patient Groups

Booij

Vree

2000

Int J Clinical Practice

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Tracheal intubation without the use of neuromuscular blocking drugs. Reply to Br J Anaesth 2018; 121: e9–10

Hunter¹

2019

British Journal of Anaesthesia

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3. Bouvet L, Stoian A, Rimmel e T, Allaouchiche B, Chassard D, Boselli E. Optimal remifentanil dosage for providing excellent intubating conditions when coadministered with a single standard dose of propofol. Anaesthesia 2009; 64: 719e26 4. Bouvet L, Stoian A, Jacquot-Laperri ere S, Allaouchiche B, Chassard D, Boselli E. Laryngeal injuries and intubating conditions with or without muscular relaxation: an equivalence study. Can J Anaesth 2008; 55: 674e84 5. Bouvet L, Chassard D, Boselli E. Tracheal intubation without muscle relaxants: large doses of opioids, small endotracheal tubes. Eur J Anaesthesiol 2006; 23: 712e3 6. Stevens JB, Wheatley L. Tracheal intubation in ambulatory surgery patients: using remifentanil and propofol without muscle relaxants.

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Should neuromuscular blocking agents always be used for tracheal intubation? Reply to Br J Anaesth 2018; 122: e8–9

Cited by 2 publications

References 6 publications

Skeletal Muscle Relaxants: Pharmacodynamics and Pharmacokinetics in Different Patient Groups

Skeletal Muscle Relaxants: Pharmacodynamics and Pharmacokinetics in Different Patient Groups

Tracheal intubation without the use of neuromuscular blocking drugs. Reply to Br J Anaesth 2018; 121: e9–10

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