Should countries switch to using five- or ten-dose rotavirus vaccines now that they are available?

Wedlock, Patrick T.; Cox, Sarah N; Bartsch, Sarah M.; Randall, Samuel; O’Shea, Kelly J; Ferguson, Marie C.; Siegmund, Sheryl S.; Lee, Bruce Y.

doi:10.1016/j.vaccine.2021.06.021

Cited by 1 publication

(1 citation statement)

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“…Various factors contribute to the wide adoption of vaccine switching globally, and decisions are frequently taken at the national or sub-national level (e.g., regional or health-care facility) to meet specific local needs. The rationale for switching vaccines on NIPs may include improving protection against infectious diseases, 1–3 optimizing budget spending, 4–6 increasing supply chain efficiency, 7 and addressing vaccine shortages. 8 , 9 …”

Section: Introductionmentioning

confidence: 99%

Implementation challenges and real-world impacts of switching pediatric vaccines: A global systematic literature review

Patikorn

Kategeaw

Perdrizet

et al. 2023

Human Vaccines & Immunotherapeutics

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Switching a vaccine for another on a pediatric national immunization program is often done for the betterment of society. However, if poorly implemented, switching vaccines could result in suboptimal transitions with negative effects. A systematic review was conducted to evaluate the existing knowledge from identifiable documents on implementation challenges of pediatric vaccine switches and the real-world impact of those challenges. Thirty-three studies met the inclusion criteria. We synthesized three themes: vaccine availability, vaccination program deployment, and vaccine acceptability. Switching pediatric vaccines can pose unforeseen challenges to health-care systems worldwide and additional resources are often required to overcome those challenges. Yet, the magnitude of the impact, especially economic and societal, was frequently under-researched with variability in reporting. Therefore, an efficient vaccine switch requires a thorough consideration of the added benefits of replacing the existing vaccine, preparation, planning, additional resource allocation, implementation timing, public–private partnerships, outreach campaigns, and surveillance for program evaluation.

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