“…However, the overall success of the process relies on comprehensive care including psychological, social and logistical concerns. The process of apheresis in children has been extensively described in several publications (19)(20)(21). In summary, a special consideration must be accorded to the preparation of the session: intake contact with the child and family, explain and re-explain the aim of the treatment by using appropriate speech, take time, prevent pain by applying lidocaine and/or using MEOPA inhalation, and warm up the patient before puncture.…”