Short- to long-term results of Ahmed glaucoma valve in the management of elevated intraocular pressure in patients with pediatric uveitis

Ekşioğlu, Ümit; Yakin, Mehmet; Sungur, Gülten; Şatana, Banu; Demirok, Gülizar; Balta, Özgür; Örnek, Firdevs

doi:10.1016/j.jcjo.2016.11.015

Cited by 25 publications

(34 citation statements)

References 26 publications

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“…( J AAPOS 2022;26: 122.e1-6122.e1-6) G laucoma drainage devices (GDDs) are commonly used in children to lower intraocular pressure (IOP) and preserve vision, especially in refractory cases. [1][2][3] The reported success rates of GDDs in the pediatric population range from 80% to 90% in the first year, but decrease over time such that many patients require additional surgeries. [1][2][3] The most commonly used GDDs are valved Ahmed and nonvalved Baerveldt implants.…”

Section: Discussionmentioning

confidence: 99%

“…[1][2][3] The reported success rates of GDDs in the pediatric population range from 80% to 90% in the first year, but decrease over time such that many patients require additional surgeries. [1][2][3] The most commonly used GDDs are valved Ahmed and nonvalved Baerveldt implants. 3 The Ahmed device has the benefits of immediate pressure-lowering effect and lower risk of postoperative hypotony, whereas the Baerveldt implant has a delayed pressure-lowering effect and a higher risk of postoperative hypotony.…”

Section: Discussionmentioning

confidence: 99%

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Ologen augmentation of Ahmed valves in pediatric glaucomas

Jacobson

Bohnsack

2022

Journal of American Association for Pediatric Ophthalmology and

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Ologen augmentation of Ahmed valves in pediatric glaucomas

Jacobson

Bohnsack

2022

Journal of American Association for Pediatric Ophthalmology and

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“…The Ahmed versus Baerveldt trial was specifically performed in adult onset glaucomas, and due to the rarity of childhood glaucomas there has not been a comparable study in the pediatric population 22. Like Baerveldts, Ahmed GDDs in children have a >80% success rate at 1 year, but by 5 years, success is often <50% which is lower than our cohort 17,35,36. Furthermore, while both Baerveldt and Ahmed GDDs have been shown to decrease IOP and the number of glaucoma medications, Ahmed implants often have a hypertensive phase between 1 and 2 months postoperatively that requires reinitiation of IOP-lowering medications 17,35,36.…”

Section: Discussionmentioning

confidence: 71%

“… 22 Like Baerveldts, Ahmed GDDs in children have a >80% success rate at 1 year, but by 5 years, success is often <50% which is lower than our cohort. 17 , 35 , 36 Furthermore, while both Baerveldt and Ahmed GDDs have been shown to decrease IOP and the number of glaucoma medications, Ahmed implants often have a hypertensive phase between 1 and 2 months postoperatively that requires reinitiation of IOP-lowering medications. 17 , 35 , 36 Due to these factors, we implanted Baerveldt GDDs in >80% of patients undergoing tube surgery during the time encompassed by the study (2012-2020).…”

Section: Discussionmentioning

confidence: 99%

Outcomes of Baerveldt Glaucoma Drainage Devices in Pediatric Eyes

Jacobson

Besirli

Bohnsack

2021

Journal of Glaucoma

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Précis: In children, Baerveldt implants showed 84% success at 1 year, but decreased to 32% at 8 years. Age, race, and glaucoma type were not risk factors for failure. Concurrent intraocular surgery was associated with complications. Purpose: Evaluate success and risk factors for failure and complications of Baerveldt glaucoma implants in children. Methods: Retrospective case series of children who underwent Baerveldt implant placement (2012-2019 by single surgeon) with ≥1 year follow-up. Ocular examination and surgical details were collected. Failure defined as intraocular pressure (IOP) <5 mm Hg or >21 mm Hg for 2 consecutive visits, need for IOP related surgery, or visually significant complication. Results: One hundred-six eyes of 76 patients underwent 110 Baerveldt placement at median 6.4 years. Baerveldt placement was combined with additional procedures in 49% with vitrectomy most common (30%). Success of first Baerveldt (per patient) was 64% at final follow-up (median 4.7 y). One-, 5-, and 8-year survival rates were 84%, 60%, and 32%, respectively. There was no difference (P=0.97) in survival between first Baerveldt and all Baerveldt surgeries. Failure of first Baerveldt was not associated with sex, age, ethnicity, prior IOP-lowering surgery, concurrent intraocular surgery, or glaucoma type. Complications occurred in 14% and were associated with concurrent surgery. Twenty-six percent required additional IOP-lowering surgery. At final follow-up, IOP and glaucoma medications were significantly decreased (P<0.0001). Eyes underwent an average of 3.8±2.3 ocular surgeries and 3.0±2.0 glaucoma surgeries. Conclusions: Baerveldt implants showed good success initially, but survival rates declined over time. No risk factors for failure of first implanted Baerveldt were identified. Concurrent surgery was associated with complications. Majority of eyes required multiple surgeries to achieve IOP control and preserve vision.

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“…Uveitic eyes are prone to developing hypotony in the early postoperative period secondary to ciliary body shutdown. [16][17][18][19] This study has several limitations. We do not categorize patients by age, so it is included all uveitic glaucoma patients, pediatric and adults.…”

Section: Reviewmentioning

confidence: 96%

Glaucoma drainage devices implantation in uveitic glaucoma: a systematic review

Emily¹,

Satolom²,

Kasih³

et al. 2021

Intisari Sains Medis

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Background: Uveitis is broadly defined as inflammation of the uvea. Glaucoma is the third most common complication of uveitis. Uveitic Glaucoma (UG) is known to be refractory, and multiple surgeries are often required for proper treatment. The purpose of this study is to determine the effectiveness of Glaucoma Drainage Device (GDD) implantation as a surgical procedure in UG patients. Method: We conducted a systematic search of electronic databases from PubMed, Science Direct, and SpringerLink using a combination of relevant keywords was performed by 5 independent reviewers. Various search terms, including 'glaucoma drainage device' , 'glaucoma drainage implants' , 'glaucoma filtration implants' , 'aqueous shunts' , 'uveitic glaucoma' , 'inflammatory glaucoma' . Result: A total of 143 articles were retrieved, but only 14 articles were eligible for data extraction. There are 631 eyes from 583 patients who had UG, 442 eyes underwent GDD implantation. Overall, intraocular pressure and the use of glaucoma medication were reduced. Mean IOP preoperative is 31.57 mmHg, and IOP postoperative is 14.48 mmHg. There is a reduction in IOP of an average of 17.09 mmHg. The number of glaucoma medications has decreased from 3.24 to 1.29 postoperatively. Conclusion: UG has been shown to be managed successfully by GDD implantation. GDD implantation may be considered a long-term effective surgical option for patients with UG.

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Short- to long-term results of Ahmed glaucoma valve in the management of elevated intraocular pressure in patients with pediatric uveitis

Cited by 25 publications

References 26 publications

Ologen augmentation of Ahmed valves in pediatric glaucomas

Ologen augmentation of Ahmed valves in pediatric glaucomas

Outcomes of Baerveldt Glaucoma Drainage Devices in Pediatric Eyes

Glaucoma drainage devices implantation in uveitic glaucoma: a systematic review

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