Short term surgical outcomes of modified deep sclerectomy with catgut implant

Choi, SeongJu; Kim, Sung S.; Kim, C Y; Hong, Young Jae

doi:10.3341/kjo.2001.15.2.113

Cited by 5 publications

(2 citation statements)

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“…But still, new implants are currently being investigated to improve outflow capacity and lower IOP postoperatively in the long terms. We scanned the Medline database and did not find any study using other materials as implants except two studies in which chromic catgut sutures were used in human trials [13, 14]. …”

Section: Introductionmentioning

confidence: 99%

Deep Sclerectomy with Various Implants: An Experimental and Histopathologic Study in a Rabbit Model

Erkılıç

Özkırış²,

Evereklioğlu³

et al. 2004

Ophthalmologica

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Background and Objective: To investigate the effectiveness of various implants used in experimental deep sclerectomy and to report tissue reactions developed to these implants histopathologically. Materials and Methods: Forty eyes of 40 New Zealand white albino rabbits underwent deep sclerectomy with various implants. The rabbits were divided into four groups; each consisted of 10 eyes. Deep sclerectomy was performed using copolymer materials in group 1, silicone materials in group 2 and chromic catgut suture in group 3. No implants were used in the control group (group 4). Clinical and histopathological examinations were performed to investigate the effectiveness of implants. Results: Mean preoperative intraocular pressure (IOP) was 14.4 ± 1.6 mm Hg in group 1, 14.5 ± 1.8 mm Hg in group 2, 13.8 ± 1.5 mm Hg in group 3 and 14.5 ± 1.2 mm Hg in group 4. The final postoperative IOPs were 10.7 ± 0.9, 10.6 ± 0.8, 13.5 ± 1.0, and 14.5 ± 1.4 mm Hg, respectively. At 2 months, the decrease in IOPs from baseline and the persistence of the filtering bleb were significantly marked in group 1 and group 2 (p < 0.001). Histopathological evaluation revealed that copolymer and silicone materials formed a smooth and regular intrascleral space. There were no foreign body reaction, tissue destruction or fibrosis in group 1 and group 2, but chromic catgut sutures caused severe fibrosis and inflammatory reaction in group 3. Mean histopathologic score of group 1, group 2, group 3 and group 4 was 0.7 ± 0.5, 0.8 ± 0.5, 2.4 ± 0.6, and 0.1 ± 0.3, respectively. Conclusion: Copolymer or silicone materials may increase the success rate of surgery by maintenance of a large and regular intrascleral space after deep sclerectomy and prevention of collapse of the flap.

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Section: Introductionmentioning

confidence: 99%

Deep Sclerectomy with Various Implants: An Experimental and Histopathologic Study in a Rabbit Model

Erkılıç

Özkırış²,

Evereklioğlu³

et al. 2004

Ophthalmologica

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“…Another cross-shaped, rigid, non absorbable polymethylmeth acrylate implant has also been developed recently [43]. Other low-cost implants, such as auto logous sclera [44,45], catgut suture material [46,47] and amniotic membrane, have been tried as implants [48].…”

Section: Nonpenetrating Deep Sclerectomymentioning

confidence: 99%

Nonpenetrating deep sclerectomy

Al-Obeidan¹

2009

Expert Review of Ophthalmology

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With the introduction of nonpenetrating deep sclerectomy (NPDS), the safety profile of filtering surgery has dramatically improved owing to the extraocular nature of the procedure that addresses abnormally increased aqueous outflow resistance in Schlemm's canal and the juxtacanalicular trabecular meshwork without entering the anterior chamber. The use of spacemaintaining devices, antimetabolites and neodymium:YAG laser goniopuncture as adjuvant tools in NPDS has improved the long-term results, so that they are comparable with those of trabeculectomy. Therefore, NPDS has become the procedure of choice in the last few years for primary open-angle glaucoma, as well as some other forms of secondary open-angle glaucoma with surgeons who have mastered the procedure. NPDS involves removal of 4 × 4-mm deep scleral flap to deroof Schlemm's canal and expose Descemet's membrane, forming a decompression space or scleral lake. Aqueous humor reaches the scleral lake via the newly created trabeculo-Descemet's membrane to be drained through different routes. The relatively long surgical learning curve remains the main disadvantage of NPDS. In this article, surgical technique, mechanism and routes of filtration, indications, contraindications, complications and results of NPDS will be discussed.

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Nonpenetrating Glaucoma Surgery

Ahmed¹,

Khan²

2009

Ophthalmology

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Short term surgical outcomes of modified deep sclerectomy with catgut implant

Cited by 5 publications

References 1 publication

Deep Sclerectomy with Various Implants: An Experimental and Histopathologic Study in a Rabbit Model

Deep Sclerectomy with Various Implants: An Experimental and Histopathologic Study in a Rabbit Model

Nonpenetrating deep sclerectomy

Nonpenetrating Glaucoma Surgery

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