Short-term memory in mice is affected by mobile phone radiation

Ntzouni, Maria; Stamatakis, Antonios; Stylianopoulou, Fotini; Margaritis, Lukas H.

doi:10.1016/j.pathophys.2010.11.001

Cited by 51 publications

(27 citation statements)

References 33 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Previous reports have suggested that RF‐EMF exposure could cause memory impairment in a mouse model [Ntzouni et al, 2011, 2013; Aldad et al, 2012], indicating a harmful effect of RF‐EMF on neurobehavioral function. In contrast, no effect of RF‐EMF exposure on spatial learning and working memory tasks was found [Sienkiewicz et al, 2000; Dubreuil et al, 2003; Maaroufi et al, 2014].…”

Section: Introductionmentioning

confidence: 99%

1950 MHz radiofrequency electromagnetic fields do not aggravate memory deficits in 5xFAD mice

Son

Jeong

Kwon³

et al. 2016

Bioelectromagnetics

View full text Add to dashboard Cite

The increased use of mobile phones has generated public concern about the impact of radiofrequency electromagnetic fields (RF‐EMF) on health. In the present study, we investigated whether RF‐EMFs induce molecular changes in amyloid precursor protein (APP) processing and amyloid beta (Aβ)‐related memory impairment in the 5xFAD mouse, which is a widely used amyloid animal model. The 5xFAD mice at the age of 1.5 months were assigned to two groups (RF‐EMF‐ and sham‐exposed groups, eight mice per group). The RF‐EMF group was placed in a reverberation chamber and exposed to 1950 MHz electromagnetic fields for 3 months (SAR 5 W/kg, 2 h/day, 5 days/week). The Y‐maze, Morris water maze, and novel object recognition memory test were used to evaluate spatial and non‐spatial memory following 3‐month RF‐EMF exposure. Furthermore, Aβ deposition and APP and carboxyl‐terminal fragment β (CTFβ) levels were evaluated in the hippocampus and cortex of 5xFAD mice, and plasma levels of Aβ peptides were also investigated. In behavioral tests, mice that were exposed to RF‐EMF for 3 months did not exhibit differences in spatial and non‐spatial memory compared to the sham‐exposed group, and no apparent change was evident in locomotor activity. Consistent with behavioral data, RF‐EMF did not alter APP and CTFβ levels or Aβ deposition in the brains of the 5xFAD mice. These findings indicate that 3‐month RF‐EMF exposure did not affect Aβ‐related memory impairment or Aβ accumulation in the 5xFAD Alzheimer's disease model. Bioelectromagnetics. 37:391–399, 2016. © 2016 The Authors Bioelectromagnetics published by Wiley Periodicals, Inc. on behalf of Bioelectromagnetics Society.

show abstract

Section: Introductionmentioning

confidence: 99%

1950 MHz radiofrequency electromagnetic fields do not aggravate memory deficits in 5xFAD mice

Son

Jeong

Kwon³

et al. 2016

Bioelectromagnetics

View full text Add to dashboard Cite

show abstract

“…Namely, one that has an absolute sense only with respect to the proper rest reference system, and otherwise completely relative with respect to all other reference systems. As for the Hamiltonian expressions (2.62), (2.67) and (2.76), one observes that they all depend strongly on the vacuum potential field function W : M 4 → R, thereby avoiding the mass problem of the classical energy expression pointed out by L. Brillouin [59]. It should be noted that the canonical Dirac quantization procedure can be applied only to the corresponding dynamical field systems considered with respect to their proper rest reference systems.…”

Section: Discussionmentioning

confidence: 94%

“…The expression (2.34) for the particle energy E 0 also appears open to question, since the potential energy qϕ, entering additively, has no affect on the particle mass m = m 0 (1 − u 2 ) −1/2 . This was noticed by L. Brillouin [59], who remarked that since the potential energy has no affect on the particle mass, this tells us that "... any possibility of existence of a particle mass related with an external potential energy, is completely excluded". Moreover, it is necessary to stress here that the least action principle (2.32), formulated with respect to the laboratory reference system K time parameter t ∈ R, appears logically inadequate, for there is a strong physical inconsistency with other time parameters of the Lorentz equivalent reference systems.…”

Section: Classical Relativistic Electrodynamics Revisitedmentioning

confidence: 97%

“…It suggests a possible serious interaction between EMF and consolidation phase of the recognition memory processes. This may imply that the primary EMF target may be the information transfer pathway connecting the entorhinal-parahippocampal regions which participate in the ORT memory task (59). A study by Heinrich S et al has led to increasing concerns on the fact that increased number of mobile phone users, exposure to radiofrequency electromagnetic fields (RF EMF) may have potential adverse effects on acute health, particularly in children and adolescents.…”

Section: Effects On Nervous System and Psycologic Disordersmentioning

confidence: 99%

See 1 more Smart Citation

Quasi-optical Systems Based on Periodic Structures

Vorobjov¹,

Shulga²,

Zhurbenko³

2011

Electromagnetic Waves

View full text Add to dashboard Cite

“…Thus far, researchers have focused on the possibility that using mobile phones may affect cognitive function. Some experimental data have been reported suggesting that RF-EMF may affect me- 5 • Hae-June Lee mory and learning impairment [11][12][13]. However, other experimental data have shown that RF-EMF does not affect memory and learning function [14,15] or even has beneficial effects [16,17].…”

Section: Introductionmentioning

confidence: 99%

The Effect of Sub-chronic Whole-Body Exposure to a 1,950 MHz Electromagnetic Field on the Hippocampus in the Mouse Brain

Son¹,

Jeong²,

Kwon³

et al. 2015

Journal of electromagnetic engineering and science

View full text Add to dashboard Cite

The increasing use of mobile phones has raised public concern about the possible biological effects of radiofrequency electromagnetic field (RF-EMF) exposure on the human brain. To investigate the potential effect of RF-EMF exposure on the brain, we examined the behaviors and hippocampal morphology of C57BL/6 mice after sub-chronic exposure to RF-EMFs with a relatively high SAR level (5.0 W/kg). We applied a 2-hour daily exposure of WCDMA 1,950 MHz using a reverberation chamber that was designed for whole-body exposure for 60 days. In the behavioral tests, RF-EMF did not alter the physical activity or long-term memory of mice. Moreover, no alteration was found in the neuronal and glial cells in the hippocampus by RF-EMFs. In this study, we showed that sub-chronic whole body RF exposure did not produce memory impairment and hippocampal morphological alteration in C57BL/6 mice.Key Words: Hippocampus, Memory, Mobile Phone, Radiofrequency Electromagnetic Field, Sub-chronic Exposure. This is an Open-Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/ by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. ⓒ

show abstract

Short-term memory in mice is affected by mobile phone radiation

Cited by 51 publications

References 33 publications

1950 MHz radiofrequency electromagnetic fields do not aggravate memory deficits in 5xFAD mice

1950 MHz radiofrequency electromagnetic fields do not aggravate memory deficits in 5xFAD mice

Quasi-optical Systems Based on Periodic Structures

The Effect of Sub-chronic Whole-Body Exposure to a 1,950 MHz Electromagnetic Field on the Hippocampus in the Mouse Brain

Contact Info

Product

Resources

About