Short-term Efficacy of Hand-Arm Bimanual Intensive Training on Upper Arm Function in Acute Stroke Patients: A Randomized Controlled Trial

Meng, Guilin; Meng, Xiuling; Tan, Yan; Yu, Jia; Jin, Aizhen; Zhao, Yanxin; Liu, Xueyuan

doi:10.3389/fneur.2017.00726

Cited by 27 publications

(33 citation statements)

References 42 publications

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“…Four studies [17, 21, 53, 54] compared the effects of BULT and UULT in subjects with acute stroke. Two studies [26, 46] compared the effects of BULT and UULT in people with sub-acute stroke.…”

Section: Resultsmentioning

confidence: 99%

“…Nine studies [15–18, 21, 27, 53, 54, 57] compared the effects of bilateral functional task training (e.g., folding a towel, lifting two cups and picking up two pegs bilaterally) and unilateral task-related training. Four studies [17, 21, 53, 54] compared these effects in people with acute stroke. Two studies [16, 18]compared the effects of bilateral functional task training and dose-matched neurodevelopmental therapy, weight-bearing exercises and unilateral functional task training.…”

Section: Resultsmentioning

confidence: 99%

“…BULT includes bilateral functional task training [15–19], bilateral robotic-assisted training [20–22] and bilateral arm training with rhythmic cueing [23–25]. Several studies have indicated the superiority of BULT over various conventional therapies (including neurodevelopmental therapy[18, 26], occupational therapy [19, 27, 28], physiotherapy [17, 21, 28] and unilateral robotic-assisted training [20]) for improving the FMA-UE, WMFT, ARAT and MAL and the ranges of motion (ROM) of the shoulder, elbow and wrist joints in people with stroke.…”

Section: Introductionmentioning

confidence: 99%

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Comparison of bilateral and unilateral upper limb training in people with stroke: A systematic review and meta-analysis

et al. 2019

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Background and objectives Bilateral upper limb training (BULT) and unilateral upper limb training (UULT) are two effective strategies for the recovery of upper limb motor function after stroke. This meta-analysis aimed to compare the improvements in motor impairment and functional performances of people with stroke after BULT and UULT. Research design and methods This systematic review and meta-analysis identified 21 randomized controlled trials (RCTs) met the eligibility criteria from CINAHL, Medline, Embase, Cochrane Library and PubMed. The outcome measures were the Fugl-Meyer Assessment of Upper Extremity (FMA-UE), Wolf Motor Function Test (WMFT), Action Research Arm Test (ARAT) and Box and Block Test (BBT), which are validated measures of upper limb function. Results Twenty-one studies involving 842 subjects with stroke were included. Compared with UULT, BULT yielded a significantly greater mean difference (MD) in the FMA-UE (MD = 2.21, 95% Confidence Interval (CI), 0.12 to 4.30, p = 0.04; I 2 = 86%, p<0.001). However, a comparison of BULT and UULT yielded insignificant mean difference (MD) in terms of the time required to complete the WMFT (MD = 0.44; 95%CI, -2.22 to 3.10, p = 0.75; I 2 = 55%, p = 0.06) and standard mean difference (SMD) in terms of the functional ability scores on the WMFT, ARAT and BBT (SMD = 0.25; 95%CI, -0.02 to 0.52, p = 0.07; I 2 = 54%, p = 0.02). Discussion and implications Compared to UULT, BULT yielded superior improvements in the improving motor impairment of people with stroke, as measured by the FMA-UE. However, these strategies did not yield significant differences in terms of the functional performance of people with stroke, as measured by the WMFT, ARAT and BBT. More comparative studies of the effects of BULT and UULT are needed to increase the reliability of these conclusions.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Comparison of bilateral and unilateral upper limb training in people with stroke: A systematic review and meta-analysis

et al. 2019

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“…The final validation of the potential candidate of repositioning rehabilitation therapy was conducted in the clinical trial of stroke patients with upper limb impairment. The trial was registered with ChiClinicalTrials.gov, number CTR-INR-1701046 [29]. To our best knowledge, there have been no other clinical studies besides ours evaluating HABIT as a therapy for adult acute stroke patients.…”

Section: Resultsmentioning

confidence: 99%

Adopting Literature-based Discovery on Rehabilitation Therapy Repositioning for Stroke

Meng

Huang

et al. 2018

Preprint

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2 18 Abstract 19 Stroke is a common disabling disease severely affecting the daily life of the 20 patients. There is evidence that rehabilitation therapy can improve the movement 21 function. However, there are no clear guidelines that identify specific, effective 22 rehabilitation therapy schemes, and the development of new rehabilitation techniques 23 has been fairly slow. One informatics translational approach, called ABC model in 24 Literature-based Discovery, was used to mine an existing rehabilitation candidate 25 which is most likely to be repositioned for stroke. As in the classic ABC model 26 originated from Don Swanson, we built the internal links of stroke (A), assessment 27 scales (B), rehabilitation therapies (C) in PubMed relating to upper limb function 28 measurements for stroke patients. In the first step, with E-utility we retrieved both 29 stroke related assessment scales and rehabilitation therapies records, and complied 30 two datasets called Stroke_Scales and Stroke_Therapies, respectively. In the next 31 step, we crawled all rehabilitation therapies co-occurred with the Stroke_Theapies, 32 named as All_Therapies. Therapies that were already included in Stroke_Therapies 33 were deleted from All_Therapies, so that the remaining therapies were the potential 34 rehabilitation therapies, which could be repositioned for stroke after subsequent 35 filtration by manual check. We identified the top ranked repositioning rehabilitation 36 therapy following by subsequent clinical validation. Hand-arm bimanual intensive 37 training (HABIT) ranked the first in our repositioning rehabilitation therapies list, 38 with the most interaction links with Stroke_Scales. HABIT showed a significant 3 39 improvement in clinical scores on assessment scales of Fugl-Meyer Assessment and 40 Action Research Arm Test in the clinical validation on upper limb function for acute 41 stroke patients. Based on the ABC model and clinical validation of the results, we put 42 forward that HABIT as a promising rehabilitation therapy for stroke, which shows 43 that the ABC model is an effective text mining approach for rehabilitation therapy 44 repositioning. The results seem to be promoted in clinical knowledge discovery. 45 46 Keywords 47 Text mining; ABC model; Stroke; Hand-arm bimanual intensive training; Upper 48 extremity 49 50 Author Summary 51 In the present study, we proposed a text mining approach to mining terms related 52 to disease, rehabilitation therapy, and assessment scale from literature, with a 53 subsequent ABC inference analysis to identify relationships of these terms across 54 publications. The clinical validation demonstrated that our approach can be used to 55 identify potential repositioning rehabilitation therapy strategies for stroke. 56 Specifically, we identified a promising rehabilitation method called HABIT 57 previously used in pediatric congenital hemiplegia. A subsequent clinical trial 58 confirmed this as a highly promising rehabilitation therapy for stroke. 4 59 Introduction 60 Stroke and rehabil...

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“…Bimanual training seeks to employ many forms of bilateral neural coupling mechanisms to enhance and harness the plasticity of the central nervous system [14,15]. However, to date, few detailed analyses of bimanual motion training have been reported, even though the effectiveness of bimanual training for recovery from motor paralysis is widely recognized [16,17]. In order to develop therapy methods, the underlying mechanisms of bimanual mechanisms need to be investigated further [18,19].…”

Section: Introductionmentioning

confidence: 99%

Influence of bimanual exercise on muscle activation in post-stroke patients

Itkonen

Costa²,

Yamasaki³

et al. 2019

Robomech J

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Brain damage due to stroke often leaves survivors with lateral functional motor deficits. Bimanual rehabilitation of the paretic arm is an active field of research aimed at restoring normal functionality by making use of the complex neural bindings that exist between the arms. In search of an effective rehabilitation method, we introduced a group of poststroke rehabilitation patients to a set of bimanual motion tasks with inter-manual coupling and phasing. The surface EMG profiles of the patients were compared in order to understand the effect of the motion conditions. The paretic arms of the patients were more strongly affected by the task conditions compared with the non-paretic arms. These results suggest that in-phase motion may activate neural circuits that trigger recovery. Coupling also had an effect on behavior, but the response of patients was divided between those whom coupling helped or hindered. which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Short-term Efficacy of Hand-Arm Bimanual Intensive Training on Upper Arm Function in Acute Stroke Patients: A Randomized Controlled Trial

Cited by 27 publications

References 42 publications

Comparison of bilateral and unilateral upper limb training in people with stroke: A systematic review and meta-analysis

Comparison of bilateral and unilateral upper limb training in people with stroke: A systematic review and meta-analysis

Adopting Literature-based Discovery on Rehabilitation Therapy Repositioning for Stroke

Influence of bimanual exercise on muscle activation in post-stroke patients

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