Short-Term Efficacy of Autologous Cellular Micrografts in Male and Female Androgenetic Alopecia: A Retrospective Cohort Study

Zari, Shadi

doi:10.2147/ccid.s334807

Cited by 10 publications

(11 citation statements)

References 38 publications

(22 reference statements)

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“…The study carried out by Zari et al [ 34 ] in a group of 140 consecutive adults with confirmed AGA sought to examine the efficacy of autologous cellular micrografts which contain HFSCs. Efficacy was evaluated 1–6 months after treatment by analyzing the change of trichometry parameters, which showed that depending on the scalp region there was an increase in the mean hair density by 4.5–7.12 hair/cm 2 .…”

Section: Resultsmentioning

confidence: 99%

Human Stem Cell Use in Androgenetic Alopecia: A Systematic Review

Krefft-Trzciniecka

Piętowska

Nowicka

et al. 2023

Cells

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Androgenetic alopecia is a condition that results in hair loss in both men and women. This can have a significant impact on a person’s psychological well-being, which can lead to a decreased quality of life. We conducted a systematic review to evaluate the efficacy of using stem cells in androgenic alopecia. The search was conducted in MEDLINE via PubMed, Web of Science, and Scopus databases. The review was performed on data pertaining to the efficacy of using different types of stem cells in androgenic alopecia: quantitative results of stem cell usage were compared to the control treatment or, different types of treatment for female and male androgenetic alopecia. Of the outcomes, the density of hair was analyzed. Fourteen articles were selected for this review. During and after treatment with stem cells, no major side effects were reported by patients with alopecia. The use of stem cells in androgenic alopecia seems to be a promising alternative to the standard treatment or it could play the role of complementary therapy to improve the effect of primary treatment. However, these results should be interpreted with caution until they can be reproduced in larger and more representative samples.

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Section: Resultsmentioning

confidence: 99%

Human Stem Cell Use in Androgenetic Alopecia: A Systematic Review

Krefft-Trzciniecka

Piętowska

Nowicka

et al. 2023

Cells

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“…ACM is an autologous cellular suspension obtained from three scalp tissue specimens disaggregated by Rigeneracons medical device (Human Brain Wave, Turin, Italy). The author, in a retrospective cohort study of 140 patients (80.7% of them female), concluded that ACM is a promising treatment in early AGA with a short-term favorable response observed in up to approximately two-thirds of patients [ 21 ]. Ruiz et al.…”

Section: Discussionmentioning

confidence: 99%

Compliance to Topical Minoxidil and Reasons for Discontinuation among Patients with Androgenetic Alopecia

Zari

2023

Dermatol Ther (Heidelb)

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Introduction: This study assessed the levels of compliance to topical minoxidil (TM) among male and female patients with androgenetic alopecia (AGA) and analyzed the factors associated with minoxidil discontinuation. Method: A retrospective study was conducted among 400 consecutive patients with AGA who presented to a dermatology clinic and who were prescribed minoxidil 2% or 5% in the past 5 years. Demographic factors, other previous treatments, and minoxidil parameters including the dose (2% or 5%), total duration of use, treatment results, and side effects were collected. Result: The mean age of the patients was 32.41 years [standard deviation (SD) 8.18], and 66.5% were female. The majority of patients (82.5%) did not receive any previous treatment for AGA. Of the total patients, 345 (86.3%) have discontinued minoxidil. Discontinuation rate showed no association with sex (p = 0.271), age

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“…In this method, autologous stem cells are obtained from skin biopsies of the patient’s scalp and then processed and reinjected as a solution into the area of hair loss on the patient’s scalp. 132 This novel technique has produced some promising data. In a 6 month follow-up study of 140 patients treated with ACM, hair density, hair thickness, and the number of follicular units increased in every region injected.…”

Section: Stem Cell Therapymentioning

confidence: 99%

Treatment of Androgenetic Alopecia: Current Guidance and Unmet Needs

Kaiser¹,

Abdin²,

Gaumond³

et al. 2023

CCID

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Androgenetic alopecia (AGA) is the most common cause of hair loss in men and women. Traditionally, topical minoxidil and oral finasteride have been the standard of care yielding mixed results. New treatments such as Low-Level Laser Therapy (LLLT), microneedling, platelet-rich plasma (PRP), and others have been extensively studied in the literature, and the purpose of this review is to provide a comprehensive discussion of the latest treatment methods and their efficacy in treating AGA. Novel therapies such as oral minoxidil, topical finasteride, topical spironolactone, botulinum toxin, and stem cell therapy offer interesting alternatives to standard of care therapies for patients. In this review, we present data from recent studies on the clinical efficacy of these treatments. Furthermore, as new treatments have emerged, clinicians have tested combination therapies to assess whether there may be a synergistic relationship between multiple modalities. While there has been a great increase in the treatments available for AGA, the quality of evidence varies greatly and there is still a great need for randomized double blinded clinical trials to adequately assess the clinical efficacy of some treatments. While PRP and LLLT have demonstrated encouraging results, standardized treatment protocols are needed to adequately inform clinicians on how to use such therapies. Given the abundance of new therapeutic options, clinicians and patients must weigh the benefits and risks of each treatment option for AGA.

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Short-Term Efficacy of Autologous Cellular Micrografts in Male and Female Androgenetic Alopecia: A Retrospective Cohort Study

Cited by 10 publications

References 38 publications

Human Stem Cell Use in Androgenetic Alopecia: A Systematic Review

Human Stem Cell Use in Androgenetic Alopecia: A Systematic Review

Compliance to Topical Minoxidil and Reasons for Discontinuation among Patients with Androgenetic Alopecia

Treatment of Androgenetic Alopecia: Current Guidance and Unmet Needs

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