Short-Term Effects of Transcatheter Aortic Valve Implantation on Left Atrial Mechanics and Left Ventricular Diastolic Function

Spethmann, Sebastian; Dreger, Henryk; Baldenhofer, Gerd; Stüer, Katharina; Saghabalyan, Davit; Müller, Eda; Hättasch, Robert; Stangl, Verena; Laule, Michael; Baumann, Gert; Stangl, Karl; Knebel, Fabian

doi:10.1016/j.echo.2012.10.002

Cited by 39 publications

(45 citation statements)

References 31 publications

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“…Recent studies reported an improvement in LA functions after the TAVI procedure in high-risk patients with systolic and diastolic dysfunction [5][6][7]. In the present study, the amelioration of LAA functions soon after the TAVI procedure may have been due to the marked and beneficial effects of the procedure on hemodynamic and echocardiographic parameters.…”

Section: Discussionsupporting

confidence: 48%

“…Recent studies that used speckle-tracking echocardiography reported an improvement in some LA functions after TAVI in high-risk AS patients [5][6][7]. Although the beneficial effect of TAVI on clinical and echocardiographic hemodynamic parameters is well known, there are no data in the literature regarding the effect of this procedure on LAA functions.…”

Section: Introductionmentioning

confidence: 88%

“…Although LAA emptying velocities were elevated after the TAVI procedure in this population, the increase was significant only in the low LVEF group. Spethmann et al [6] demonstrated an improvement only in reservoir and conduit functions in the early period after the TAVI procedure. However, their study contained no information on the relationship between reservoir and conduit functions and LVEF.…”

Section: Discussionmentioning

confidence: 99%

“…Spethmann et al [7] demonstrated that a global and regional LV and LA mechanics improved 12 months after TAVI. LA function was evaluated with speckle-tracking echocardiography in previous TAVI studies [5][6][7]. To the best of our knowledge, this is the first study to assess LAA functions after TAVI procedure in patients with severe AS.…”

Section: Discussionmentioning

confidence: 99%

See 3 more Smart Citations

Short-term effects of transcatheter aortic valve implantation on left atrial appendage function

Aslan

Gül

Çakmak³

et al. 2015

Cardiol J.

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Section: Discussionsupporting

confidence: 48%

Section: Introductionmentioning

confidence: 88%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Short-term effects of transcatheter aortic valve implantation on left atrial appendage function

Aslan

Gül

Çakmak³

et al. 2015

Cardiol J.

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“…Spethmann et al [27] reported an acute improvement in the reservoir and conduit function of the LA accompanied by improvement of LV diastolic function within 8 days of the procedure. Aslan et al [28] reported that TAVI is associated with improved LA appendage function, especially in patients with a marked diastolic dysfunction.…”

Section: Discussionmentioning

confidence: 99%

Conduction Abnormalities after Transcatheter Aortic Valve Implantation and Diastolic Dysfunction

Priesler

Biner²,

Finkelstein³

et al. 2016

Cardiology

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Objectives: Transcatheter aortic valve implantation (TAVI) is frequently associated with the development of conduction abnormalities. We assessed the effect of conduction abnormalities on diastolic function following TAVI. Methods: In total, 101 consecutive post-TAVI patients were included, each with echocardiographic follow-up at 1 and 6 months. Diastolic properties were correlated with the occurrence of a long PR interval and wide QRS, and their change from baseline. The measured diastolic parameters included E/A ratio, E wave deceleration time, E wave to e′ ratio, left atrial (LA) volume, and systolic pulmonary artery pressure (SPAP). The clinical outcome was all-cause mortality. Results: Overall, TAVI was associated with a consistent decrease in SPAP at the 1- and 6-month follow-up. LA volumes were increased at 1 month post-TAVI in patients with a wide compared to normal QRS (p = 0.03) and at 6 months in patients with a normal compared to prolonged PR (p = 0.03). PR prolongation above 40 ms was associated with lower SPAP at the 1- but not 6-month follow-up. Survival was not influenced by conduction abnormalities. Conclusions: TAVI is associated with a reduction in SPAP. A postprocedural wide QRS and normal PR interval may unfavorably influence the left-sided filling performance, resulting in an increased LA volume. Other diastolic parameters, as well as survival, are not significantly affected by postprocedural conduction abnormalities.

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Echocardiographic determinants of LV functional improvement after transcatheter aortic valve replacement

Chen

Nawaz

Fox

et al. 2015

Cathet Cardio Intervent

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Short-Term Effects of Transcatheter Aortic Valve Implantation on Left Atrial Mechanics and Left Ventricular Diastolic Function

Cited by 39 publications

References 31 publications

Short-term effects of transcatheter aortic valve implantation on left atrial appendage function

Short-term effects of transcatheter aortic valve implantation on left atrial appendage function

Conduction Abnormalities after Transcatheter Aortic Valve Implantation and Diastolic Dysfunction

Echocardiographic determinants of LV functional improvement after transcatheter aortic valve replacement

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