Short-Term Effects of Intra-Articular Hyaluronic Acid Administration in Patients with Temporomandibular Joint Disorders

Abstract

The study described in this paper was conducted to assess the short-term outcomes of intra-articular administration of hyaluronic acid in patients with symptoms of temporomandibular joint disorders. A group of 40 patients suffering from temporomandibular joint disorders underwent a series of hyaluronic acid intra-articular injections. Questionnaires and clinical examinations were conducted to assess stress exposure of the subjects and to evaluate short-term treatment outcomes, i.e., reducing joint and muscle pain and increasing the mobility of the mandible. A weak positive correlation between stress exposure and pain was observed. As a result of treatment, 61% of subjects revealed a total reduction of muscle pain, while joint pain completely resolved in 88% of patients. Mandibular mobility increased by 11%, 31%, 9%, and 11% regarding opening, protrusive, and lateral right and left movements, respectively. The study confirms the short-term effectiveness of intra-articular administration of hyaluronic acid on reducing joint and muscle pain in patients with articular disc displacement. The treatment positively affected the mobility of the mandible in all directions. The verification of late treatment effects of hyaluronic acid viscosupplementation requires the continuation of the research.

Intramuscular Injections and Dry Needling within Masticatory Muscles in Management of Myofascial Pain. Systematic Review of Clinical Trials

“…However, we have not noted any studies showing an increased infection potential over the course of needling in the masticatory muscles, compared to other procedures involving punctures. Consideration should be given to the possibility of intentionally weakening the activity of the masticatory muscles or eliminating muscle pain in pathologies manifested by abnormal work of the temporomandibular joint, including fractures of the mandible or its defects, e.g., missing teeth [ 74 , 75 , 76 ]. Of particular importance among mandibular fractures may be intracapsular fractures of the mandibular head, the treatment of which may be highly traumatizing to the structures of the temporomandibular joint, and thus, affect the functioning of the entire stomatognathic system [ 77 , 78 ].…”

Variants and Modifications of the Retroauricular Approach Using in Temporomandibular Joint Surgery: A Systematic Review

“…The assessment of temporomandibular joint dysfunctions should be performed based on the clinical examination and additional imagining, such as magnetic resonance imaging [ 36 , 37 ]. Furthermore, arthroscopy may be used as a supplement to these methods [ 36 , 38 ]. Therefore, the indications for RA are purely therapeutic.…”

Evaluating the Effect of the Injectable PRF in comparison with the hyaluronic acid as an Intra-articular Medication Following Arthrocentesis in the Treatment of Internal Derangement

“…Arthrocentesis either followed with intra-articular injections, or not has gained a large deal of interest [7,10,[14][15][16] . Arthrocentesis has its therapeutic effect by releasing adhesions, releasing intraarticular negative pressure, and washing out inflammatory mediators such as cytokines; thereby it relieves pain and improves joint function [17][18][19][20][21][22] . Arthrocentesis might be performed alone or followed by intra-articular injection of variant substances such as hyaluronic acid (HA), corticosteroids, morphine, platelet-derived growth factor [PDGF] [10,14,15,[21][22][23][24] .…”

“…Arthrocentesis has its therapeutic effect by releasing adhesions, releasing intraarticular negative pressure, and washing out inflammatory mediators such as cytokines; thereby it relieves pain and improves joint function [17][18][19][20][21][22] . Arthrocentesis might be performed alone or followed by intra-articular injection of variant substances such as hyaluronic acid (HA), corticosteroids, morphine, platelet-derived growth factor [PDGF] [10,14,15,[21][22][23][24] . Hyaluronic acid (HA) is the main constituent of the synovial fluid that is naturally released by the synovial cells into the joint and has a pivotal role in lubrication.…”

“…Hyaluronic acid (HA) is the main constituent of the synovial fluid that is naturally released by the synovial cells into the joint and has a pivotal role in lubrication. As a therapeutic material for intra-articular injection, it has been proved to reduce pain and improve the mouth opening [21][22][23][24] . Another intra-articular injection material which is the plasma rich in platelet-derived growth factors (PRGFs) has been employed to regenerate the synovial tissues and the other degenerated tissues in the joint.…”